Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sharp HealthCare
With
Sharp Mary Birch Hospital for Women & Newborns
Loma Linda University
University of Pittsburgh
Providence Hospital
University of Alabama at Birmingham
University of Alberta
University College Cork
University of Ulm
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Christiana Care Health Services
Sharp Grossmont Hospital
University of Utah
University of Mississippi Medical Center
PIH Health Good Samaritan Hospital
University of California, Irvine
Children's Hospital Medical Center, Cincinnati
Cook County Health
St. Louis University
LAC+USC Medical Center
Aim 1. Compare the incidence of severe intraventricular hemorrhage (IVH) and/or death in premature newborns \<33 weeks gestational age (GA) delivered by C/S receiving UCM to those receiving DCC.
Hypothesis1: First demonstrate infants in the UCM group are not inferior to the DCC group (reject H10).
Hypothesis2: If H1 is true, demonstrate lower incidence of severe IVH and/or death in UCM infants compared to DCC.
Aim 2. Compare the safety and efficacy profiles of premature newborns \<33 weeks GA delivered by C/S receiving UCM vs. DCC during their hospitalization.
Hypothesis3: UCM group will have a decreased need for resuscitation interventions with no differences in bilirubin or polycythemia compared to DCC.
Hypothesis4: UCM group will have improved blood pressures in the first 24 hours of life compared to DCC.
Aim 3 (exploratory). To compare the outcomes of premature newborns \<33 weeks GA delivered by C/S (Cesarean section) (from Aims 1 and 2) with those born by V/D (vaginal delivery) receiving UCM or DCC.
Age
0–0
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
23 to 32 +6 Gestational age (currently enrolling 29 to 32+6 weeks)
Multiples without Twin-to-twin Transfusion Syndrome (TTTS)
You may not be if
Congenital anomalies
Major cardiac defects
Placental abruption or previa with hemorrhage
Cord prolapse
Hydrops
Bleeding Accreta
Monochorionic multiples with evidence of TTTS
Fetal or maternal risk (i.e. compromise)
Parents declined study
Unlikely to return for 2 yr Follow Up
Clareo Health | Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2