Clinical Trials in Pittsburgh

Showing 2221-2240 of 10,050 trials

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

NCT06386029

The goal of this pilot intervention study is to examine the feasibility and acceptability of a novel bedtime manipulation protocol called "The Power Down" for autistic youth, ages 6-10. The main questions it aims to answer are: 1. Is the Power Down feasible for caregivers to do each night? 2. Do the families find the Power Down an acceptable intervention to address their child's difficulties settling down to fall asleep?

AutismSleep Disturbance

University of Pittsburgh10 participantsStarted Jul 2025

Pittsburgh, Pennsylvania, United States

RECRUITING< 1 mile

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

NCT06503367

The goal of this observational study is to understand how young children with LAMA2-related dystrophy move and change over time. We will also learn about how this condition impacts other body systems. Participants will undergo: * Neuromuscular assessments * Blood collections * Swallowing and breathing assessments * Questionnaires

LAMA2-MD \(Merosin Deficient Congenital Muscular Dystrophy, MDC1A\)

Nationwide Children's Hospital44 participantsStarted May 2025

Los Angeles, California, United States • Stanford, California, United States • Chicago, Illinois, United States +11 more locations

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

Find Trials by Condition in Pittsburgh

Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)

Remote Mindfulness Training Following Early Life Adversity

Prevalence of Multidrug Resistant Micro-organism Carriage in Patients Undergoing an ERCP in Four Different Countries

Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer

A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

A Study to Assess the Safety, Tolerability, and Immunogenicity of RSVpreF in Adults at High Risk of Severe RSV Disease

Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Patients With High-Grade Upper Tract Urothelial Carcinoma

A Study to Investigate Safety and Tolerability of NDX-3315 and NDX-3324 in Healthy Participants and Patients With Eosinophilic Esophagitis

A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC)

Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors