Clinical Trials in Philadelphia

Showing 1781-1800 of 9,968 trials

Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma

NCT04935229

This study is an open-label, phase 1/1b study of the pressure-enabled hepatic artery infusion of SD-101, a TLR 9 agonist, alone or in combination with intravenous checkpoint blockade in adults with metastatic uveal melanoma.

Metastatic Uveal Melanoma in the Liver

TriSalus Life Sciences, Inc.67 participantsStarted Aug 2021

Los Angeles, California, United States • Stanford, California, United States • Denver, Colorado, United States +7 more locations

RECRUITINGPhase 2< 1 mile

PMT for MDRO Decolonization

NCT05632315

This is a randomized, open label, comparative Phase II trial being conducted to determine whether fecal microbiota transplant using Penn Microbiome Therapy (PMT) products helps standard therapy eradicate antibiotic-resistant bacteria.

Multidrug Resistant Bacterial InfectionEnterobacteriaceae InfectionsPseudomonas Aeruginosa+2 more

University of Pennsylvania150 participantsStarted Aug 2024

Atlanta, Georgia, United States • St Louis, Missouri, United States • Philadelphia, Pennsylvania, United States

Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma

PMT for MDRO Decolonization

Find Trials by Condition in Philadelphia

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

Study of Fordadistrogene Movaparvovec in Early Stage Duchenne Muscular Dystrophy

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)

Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer

Study of RP-3500, Camonsertib, in Advanced Solid Tumors

Hearing Impairment, Strategies and Outcomes in VA Emergency Departments

Open-label Long-term Study of Adjunctive Brivaracetam in Pediatric Subjects With Epilepsy

A Study to Evaluate the Safety and Efficacy of AV-1 Against Dengue Virus 3 (DENV-3) Infection

A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes

Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories