Clinical Trials in Philadelphia

Showing 1621-1640 of 9,968 trials

Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants

NCT03169881

Study Hypothesis: Preterm infants administered weekly Darbe during the neonatal period will have improved neurocognitive outcome at 22-26 months compared to placebo

NeurocognitiveNeuroprotectiveNeonatal+1 more

NICHD Neonatal Research Network650 participantsStarted Sep 2017

Birmingham, Alabama, United States • Palo Alto, California, United States • Atlanta, Georgia, United States +13 more locations

Active Not RecruitingPhase 1/2< 1 mile

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

NCT04180371

This clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of EphA2. The main goals of this study are to: * Find the recommended dose(s) of BT5528 that can be given safely to participants alone and in combination with nivolumab * Learn more about the side effects of BT5528 * Learn about how effective BT5528 is for the treatment of ovarian cancer, urothelial/bladder cancer, lung cancer (NSCLC), triple-negative breast cancer, head and neck cancer (HNSCC), and gastric/upper gastrointestinal cancer. * Learn more about BT5528 therapy alone and in combination with nivolumab.

Advanced Solid Tumor Historically Known for High EphA2 ExpressionUrothelial CancerOvarian Cancer+4 more

BicycleTx Limited288 participantsStarted Nov 2019

Encinitas, California, United States • Orange, California, United States • Denver, Colorado, United States +25 more locations

Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

Find Trials by Condition in Philadelphia

AI-informed Colorectal Cancer (CRC) Screening Navigation vs. Standard of Care Among Screening-naive Penn Medicine Patients 45-49 Years Old to Increase CRC Screening Uptake

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)

Delirium in Children Undergoing Stem Cell Transplantation

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Evaluating Home Testing Devices for the Management of Glaucoma

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a New Formulation of Cabotegravir Long-Acting Administered Intramuscularly in a 4-month Dosing Interval (Q4M)

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia

Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial