Clinical Trials in Philadelphia

Showing 7941-7960 of 15,860 trials

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

NCT02982941

This study is a Phase 1, open-label, dose escalation and cohort expansion trial designed to characterize the safety, tolerability, PK, PD, immunogenicity and preliminary antitumor activity of enoblituzumab administered IV on a weekly schedule for up to 96 doses (approximately 2 years) in children and young adults with B7-H3-expressing relapsed or refractory malignant solid tumors.

NeuroblastomaRhabdomyosarcomaOsteosarcoma+3 more

MacroGenics25 participantsStarted Dec 2016

Palo Alto, California, United States • Bethesda, Maryland, United States • Philadelphia, Pennsylvania, United States +3 more locations

COMPLETED< 1 mile

Opioid Taper Study

NCT03912298

The purpose of this study is to determine the effect of opioid taper on pain sensitivity in patients with chronic pain. In a well-characterized sample of men and women with chronic neuropathic pain on high-dose opioid therapy, experimental pain responses (cold-pressor, quantitative sensory testing) will be serially described over the course of and following an individualized opioid taper. In addition, functional improvements and subject-level predictors of response will be described.

Chronic Pain

University of Pennsylvania7 participantsStarted Apr 2019

Philadelphia, Pennsylvania, United States

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

Opioid Taper Study

Find Trials by Condition in Philadelphia

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

Automated Harness Tightener for Child Safety Seat

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias

Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma

Feasibility of Telemedicine Medical Abortion

Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens

Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)

IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

Improving Critical Congenital Heart Disease Screening With Addition of Perfusion Measurements

A Multi-Center Trial to Study Acute Liver Failure in Adults

SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation

Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.

Study to Determine Safety and Dose of NJH395 in Non-breast HER2+ Advanced Cancer

Awareness, Care & Treatment In Obesity Management - An International Observation Among Teens (ACTION Teens)