Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Shionogi
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Having refractory chronic cough (including unexplained chronic cough) for at least 1 year.
If female and of childbearing potential, agreement to use one of the allowed contraceptive methods.
Capable of giving signed informed consent.
You may not be if
Currently smokes or uses potentially irritating inhalational agents (eg, e-cigarettes, smokeless cigarettes, vaping); stopped smoking or using potentially irritating inhalational agents within the last year; or has a smoking history of 20 pack-years or more.
Has chronic obstructive pulmonary disease or uncontrolled asthma.
Has a clinically unstable medical condition.
History of or ongoing significant psychiatric disorder.
History of respiratory tract infection or significant change in lung function or a pulmonary condition in the last 4 weeks.
History of malignancy in the last 5 years.
History of severe drug allergy.
History of alcohol or drug abuse in the last year or currently uses any form of marijuana or illicit drugs.
Has a clinically significant finding on a chest x-ray or chest computed tomography (CT) scan in the last year.
Has systolic blood pressure \> 160 mm Hg or diastolic blood pressure \> 90 mm Hg.
Received S-600918 previously.
Received an investigational drug in the last 3 months.
Received an angiotensin converting enzyme (ACE) inhibitor in the last 3 months or requires such treatment.
Has a positive serologic test for human immunodeficiency virus (HIV) antigen or antibody, hepatitis B virus surface antigen, or hepatitis C virus ribonucleic acid (RNA).
If female, pregnant or trying to become pregnant or breastfeeding.
Clareo Health | Evaluation of S-600918 in Adults With Refractory Chronic Cough
