Clinical Trials in Philadelphia

Showing 7381-7400 of 15,860 trials

Phase II Safety and Efficacy Study of 18FDOPA PET-CT in Children With Hyperinsulinemic Hypoglycemia

NCT01468454

Children with congenital hyperinsulinism (CHI) have low blood sugar, and some of these children may require surgery to remove part or all of their pancreas. In this study, researchers will test how well a radioactive drug, 18-labeled L-fluorodeoxyphenylalanine (called F-DOPA) can detect a form of hyperinsulinism (focal HI) that may be cured by surgery. Eligible participants in this study will have positron emission tomography/computerized tomography (PET/CT) scans with F-DOPA prior to surgery.

Congenital Hyperinsulinism (CHI)Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)

Children's Hospital of Philadelphia130 participantsStarted Jan 2009

Philadelphia, Pennsylvania, United States

WITHDRAWNPhase 2< 1 mile

Derivatives of Omega-3 HUFA as Biomarkers of Traumatic Brain Injury

NCT02990091

This is a Phase 2 clinical trial designed to obtain data on relationships between potentially therapeutic doses of n-3 HUFA (highly unsaturated fatty acids) and their bioactive molecular derivatives, synaptamide, 17-hydroxy-DHA, and D-series resolvins, on clinical outcomes after TBI.

TBI

University of PennsylvaniaStarted Jan 2017

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver Cirrhosis

NCT03486912

This is a study of experimental medication BMS-986036 given to adults with Nonalcoholic Steatohepatitis (NASH; the buildup of fat and inflammation in the liver that is not caused by alcohol) and liver cirrhosis (liver damage characterized by normal liver tissue being replaced by scar tissue).

Hepatic CirrhosisLiver FibrosisNonalcoholic Fatty Liver Disease (NAFLD)+1 more

Bristol-Myers Squibb155 participantsStarted Jun 2018

Madison, Alabama, United States • Chandler, Arizona, United States • Phoenix, Arizona, United States +88 more locations

Phase II Safety and Efficacy Study of 18FDOPA PET-CT in Children With Hyperinsulinemic Hypoglycemia

Derivatives of Omega-3 HUFA as Biomarkers of Traumatic Brain Injury

A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver Cirrhosis

Find Trials by Condition in Philadelphia

Safety and Effectiveness Study of the Reflection Ceramic Acetabular System

PKUDOS: Phenylketonuria (PKU) Demographic, Outcomes, and Safety Registry

Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention

Open-Label Safety Study of AXS-05 in Subjects With Depression

A Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Chronic Migraine Prevention

Safety and Efficacy of Nerinetide (NA-1) in Subjects Undergoing Endovascular Thrombectomy for Stroke

Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19)

A Study to Evaluate Efficacy and Safety of BAC in Patient With Alzheimer's Disease or Vascular Dementia

A Clinical Trial of Buparlisib and Ibrutinib in Lymphoma

A Phase 1 Study to Evaluate MEDI4736 in Combination With Tremelimumab

NY-ESO-1 Plasmid DNA (pPJV7611) Cancer Vaccine

Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma

Study of Lanreotide Autogel 120 mg in Patients With Non-functioning Entero- Pancreatic Endocrine Tumour

A Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)

Clot Dissolving Treatment for Blood Clots in the Lungs