Clinical Trials in Philadelphia

Showing 6161-6180 of 20,904 trials

Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer

NCT03754933

Primary Objective: The primary objective of the study is to evaluate the safety of repeat administration of a dose level of Ad/PNP plus fludarabine phosphate (F-araAMP) which demonstrated anti-tumor activity in patients with advanced head and neck cancer in a completed phase I study. Secondary Objective: The secondary objective is to evaluate the antitumor activity of repeat administration of Ad/PNP plus F-araAMP. FDA Office of Orphan Drugs Division is a source of funding for the overall project.

Recurrent Head and Neck Cancer

GeoVax, Inc.10 participantsStarted Feb 2019

Stanford, California, United States • Atlanta, Georgia, United States • Philadelphia, Pennsylvania, United States

TERMINATEDPhase 2/3< 1 mile

A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention

NCT04804033

The purpose of this is study is to compare the efficacy of BHV-3500 (zavegepant) to placebo as a preventive treatment for migraine, as measured by the reduction in the number of migraine days per month.

Migraine

Pfizer1,753 participantsStarted Mar 2021

Phoenix, Arizona, United States • Tucson, Arizona, United States • Canoga Park, California, United States +113 more locations

Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer

A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention

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MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Co-Administration of Roluperidone and Olanzapine in Adult Subjects With Moderate to Severe Negative Symptoms of Schizophrenia

Optimal Post Tpa-Iv Monitoring in Ischemic Stroke

Study of NIS793 and Other Novel Investigational Combinations With SOC Anti-cancer Therapy for the 2L Treatment of mCRC

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

Outcome of Patients with Severe Functional TR According to Medical, Transcatheter or Surgical Treatment

Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors

Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Kids FACE FEARS Comparative Effectiveness Research

Noninvasive Monitoring of Uterine Activity and Fetal Heart Rate

Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome

Walking and mHealth to Increase Participation in Parkinson Disease

Antibiotic Prophylaxis Before Shock Wave Lithotripsy

Efficacy of Emotionally Focused Therapy Among Spanish Speaking Couples