Clinical Trials in Philadelphia

Showing 6061-6080 of 15,860 trials

CASCARA: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone

NCT03934840

This is a phase II clinical trial in patients with metastatic castration sensitive prostate cancer. The objective of the study is to determine the efficacy and further define the safety of the treatment combination. This study will evaluate dose levels of carboplatin AUC 4 with cabazitaxel 20 mg/m2. Patients will be treated with the combination of ADT and carboplatin and cabazitaxel for 6 cycles. After 6 cycles of chemotherapy, they will start abiraterone with ADT. The primary objective is to determine the percent of subjects that have no PSA or radiographic progression at 1 year. Secondary objectives will include determining the progression-free survival, time to PSA nadir and time to PSA progression of carboplatin and cabazitaxel in combination with ADT.

Prostate Cancer

Masonic Cancer Center, University of Minnesota22 participantsStarted Oct 2019

Phoenix, Arizona, United States • Chicago, Illinois, United States • Chicago, Illinois, United States +5 more locations

COMPLETEDPhase 2< 1 mile

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

NCT03664960

This is a Phase 2, open-label, extension study to assess the safety and tolerability of AK002, given monthly for up to 26 doses.

Eosinophilic GastritisEosinophilic GastroenteritisEosinophilic Duodenitis

Allakos Inc.58 participantsStarted Nov 2018

Phoenix, Arizona, United States • Scottsdale, Arizona, United States • Ventura, California, United States +14 more locations

CASCARA: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Find Trials by Condition in Philadelphia

HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network

OCS Lung System EXPAND II Trial

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

Prevalence of PD-L1 Expression in Patients With Advanced Urothelial Carcinoma

Efficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast Cancer

A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer

High Fiber in Parkinson's Disease

A Study to Assess BMS-986207 in Combination With Nivolumab and Ipilimumab as First-line Treatment for Participants With Stage IV Non-Small Cell Lung Cancer

A Study to Compare Bempegaldesleukin (BEMPEG: NKTR-214) Combined With Nivolumab and Tyrosine Kinase Inhibitor (TKI) to Nivolumab and TKI Alone in Participants With Previously Untreated Kidney Cancer That is Advanced or Has Spread

Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast

Pilot Prospective Study: Long-term Health of Living Kidney Donors

Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19

A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)

Cardionomic STOP-ADHF Study