Clinical Trials in Philadelphia

Showing 5801-5820 of 15,860 trials

Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound

NCT03245255

This study will use contrast echocardiography to assess the accuracy of a new non-invasive imaging method for subharmonic aided pressure estimation (SHAPE) compared to simultaneously acquired intra-cardiac pressures measured invasively during cardiac catheterization. This study is designed to verify that contrast echocardiography using the SHAPE method, already proven in a canine model and tested in a human pilot study can be used as a surrogate for cardiac catheterization with sufficient accuracy to allow clinical applicability in humans.

Cardiac CatheterizationBlood PressureHeart Ventricles+2 more

Thomas Jefferson University80 participantsStarted Dec 2017

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

A Study to Evaluate Ketamine for the Treatment of Rett Syndrome

NCT03633058

This 2 cohort, sequential, ascending dose study will assess the safety, tolerability and efficacy of oral ketamine dosed in a single 5-day BID regimen in addition to placebo, in a 4-week cross-over design in patients with Rett Syndrome. Approximately 12 patients per cohort are anticipated to participate for approximately 8-10 weeks at approximately 7 US study centers.

Rett Syndrome

Rett Syndrome Research Trust23 participantsStarted Mar 2019

Birmingham, Alabama, United States • Aurora, Colorado, United States • Chicago, Illinois, United States +4 more locations

Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound

A Study to Evaluate Ketamine for the Treatment of Rett Syndrome

Find Trials by Condition in Philadelphia

DC Vaccine in Colorectal Cancer

Use of Oxandrolone to Promote Growth in Infants With HLHS

Diuretic Comparison Project

Nexplanon Use in Women Primarily Choosing a Combined Oral Contraceptive

Resolution of Pudendal Neuralgia in Chronic Pelvic Pain Using a Novel Biologic Therapy

Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management

A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Efficacy Study of Two Influenza Vaccines and Placebo in Healthy Adult Subjects

Safety and Efficacy of SP-103 in Subjects With Moderate to Severe Acute Lower Back Pain

IN.PACT™ AV Access IDE Study

Predictors of Severe COVID-19 Outcomes

Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

Clinical Study to Investigate the Safety and Effectiveness of RECELL for Repigmentation of Stable Vitiligo Lesions

Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)

Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency