Clinical Trials in Philadelphia

Showing 5461-5480 of 15,860 trials

Investigating the Effect of Obicetrapib on Lipoprotein Metabolism

NCT05972278

To determine the treatment effect with obicetrapib (10 mg) on the fractional catabolic rate (FCR) of apolipoprotein (apo) B100 in low-density lipoprotein (LDL).

Lipid Metabolism

NewAmsterdam Pharma22 participantsStarted Dec 2023

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastoma

NCT03661723

This research study is studying pembrolizumab and re-irradiation as possible treatments for glioblastoma. The drugs involved in this study are: * Pembrolizumab * Radiation * Bevacizumab, an FDA-approved drug for treating recurrent glioblastoma multiforme (GBM)

Glioblastoma

Dana-Farber Cancer Institute60 participantsStarted Sep 2018

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Boston, Massachusetts, United States +2 more locations

TERMINATEDPhase 3< 1 mile

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

NCT03955146

This is a Phase 3 trial to evaluate the efficacy and safety of 30 milligrams (mg)/kilogram (kg) intravenous (IV) infusions of pamrevlumab administered every 3 weeks as compared to placebo in participants with IPF.

Idiopathic Pulmonary Fibrosis

Kyntra Bio393 participantsStarted Jun 2019

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +122 more locations

Investigating the Effect of Obicetrapib on Lipoprotein Metabolism

Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastoma

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Find Trials by Condition in Philadelphia

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer

Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)

AI ENRICH - AI Detection of ICH

PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

VTX958 Versus Placebo for the Treatment of Moderate to Severe Psoriasis

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

An Open-Label Extension Study for Patients With Duchenne Muscular Dystrophy Who Participated in Studies of SRP-5051 (Vesleteplirsen)

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)

A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma

Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry

Acupuncture for Preterm Infants Requiring Eye-exam