Clinical Trials in Philadelphia

Showing 4961-4980 of 15,860 trials

Effect of rTMS on Anxiety

NCT03993509

Given the overall lack of treatment adherence/efficacy, side effects of drugs, and the substantial burden of anxiety disorders on the individual and on the national healthcare system, there is a critical need for mechanistic research into the CNS mechanisms that underlie these disorders. Accordingly, the objective of this grant is to use noninvasive neuromodulation to causally identify the key neural mechanisms that mediate the cognitive symptoms of anxiety. This project is relevant to public health because it has the potential to lead to novel repetitive transcranial magnetic stimulation treatments for pathological anxiety.

AnxietyFearAnxiety and Fear

University of Pennsylvania68 participantsStarted Oct 2019

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2/3< 1 mile

Novel Experimental COVID-19 Therapies Affecting Host Response

NCT04924660

The overarching goal of the Master Protocol is to find effective strategies for inpatient management of patients with COVID-19. Therapeutic goals for patients hospitalized for COVID-19 include hastening recovery and preventing progression to critical illness, multiorgan failure, or death. Our objective is to determine whether modulating the host tissue response improves clinical outcomes among patients with COVID-19. The primary analysis will include data from NCT05593770.

COVID-19SARS-CoV-2 InfectionCoronavirus Infection

Sean Collins1,060 participantsStarted Jul 2021

Birmingham, Alabama, United States • Chandler, Arizona, United States • Los Angeles, California, United States +48 more locations

Effect of rTMS on Anxiety

Novel Experimental COVID-19 Therapies Affecting Host Response

Find Trials by Condition in Philadelphia

Building Employment Skills Through Therapy for Veterans

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

ACP-104 in Acutely Psychotic Subjects With Schizophrenia

Stereotactic Laser Ablation for Temporal Lobe Epilepsy (Slate)

Evaluation of Four Injectable Neuromodulators in the Glabella Area Glabella Area

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

Verapamil for Neuroprotection in Stroke

Assessment of Financial Difficulty in Participants with Chronic Lymphocytic Leukemia and Multiple Myeloma

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

International EXPAND Heart Pivotal Trial

ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection

Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation

The Gilenya Pregnancy Registry

Extension to the MAGNIFY MS Trial on Mavenclad® (Magnify MS Extension)

Polyethylene Wear Particle Analysis of TKA

Non-Complex Biliary Stones DSC vs ERC

International obServational sTudy on AiRway manaGement in operAting Room and Non-operaTing Room anaEsthesia