Clinical Trials in Philadelphia

Showing 3201-3220 of 20,904 trials

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

NCT05721326

The goal of this sequential study design is to increase genetic testing in those meeting national clinical guidelines. The main question it aims to answer is: which intervention is most effective in uptake of genetic testing for the target population? Participants will receive genetic testing and counseling that may initiate life-saving screenings.

Genetic Predisposition to DiseaseBreast Cancer FemaleOvarian Cancer+4 more

Abramson Cancer Center at Penn Medicine1,330 participantsStarted May 2023

Philadelphia, Pennsylvania, United States

COMPLETEDNA< 1 mile

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

NCT04452149

The ALLEVIATE-HF study is a prospective, randomized, controlled, blinded, multi-site, interventional, investigational device exemption (IDE) pivotal study. The purpose of the study is to demonstrate the safety and efficacy of a patient management pathway that utilizes an integrated device diagnostic-based risk stratification algorithm to guide patient care in subjects with NYHA class II and III heart failure, and to demonstrate the safety of the Reveal LINQ™ system and procedure in the study population.

Heart Failure NYHA Class IIHeart Failure NYHA Class III

Medtronic Cardiac Rhythm and Heart Failure826 participantsStarted Sep 2020

Mesa, Arizona, United States • Jonesboro, Arkansas, United States • Mission Viejo, California, United States +50 more locations

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

Find Trials by Condition in Philadelphia

A Study of Zetomipzomib (KZR-616) in Patients With Autoimmune Hepatitis (PORTOLA)

A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

Optimize PRO Study

Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis

A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).

A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension

Study of Efficacy and Safety of QAW039 When Added to Standard-of-care Asthma Therapy in Patients With Uncontrolled Asthma

Data Collection for the Validation of an Artificial Intelligence Software to Support Musculoskeletal Ultrasound Examination

The PRECISION Trial (Profiling Early Breast Cancer for Radiotherapy Omission): A Phase II Study of Breast-Conserving Surgery Without Adjuvant Radiotherapy for Favorable-Risk Breast Cancer

Liver Cirrhosis Network Cohort Study

The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

A Study in Patients With Mixed Dyslipidemia

A Single Arm Study Evaluating the Efficacy, Safety and Tolerability of Ofatumumab in Patients With Relapsing Multiple Sclerosis

Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan.

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia