History of pelvic radiation treatment

History of urethral diverticula

History of urethral sling or anterior prolapse repair

Treatment with urethral bulking agents and/or other SUI procedure or surgery within the 6 months prior to the Screening Visit

Known vesicoureteral reflux, vaginal prolapse beyond the introitus, or other significant pelvic floor abnormalities

Urinary incontinence of neurogenic etiology

Morbidly obese (defined as 100 pounds over ideal body weight, or body mass index 40 or greater)

Chronic hepatitis

Hepatic cirrhosis

Evidence of active infection with hepatitis B or hepatitis C

History of human immunodeficiency virus (HIV) infection

Subjects with a history of breast or endometrial cancer

Study to Assess Enobosarm (GTx-024) in Postmenopausal Women With Stress Urinary Incontinence