Clinical Trials in Philadelphia

Showing 2981-3000 of 20,904 trials

Longitudinal Study for Relapsing Polychondritis

NCT04919538

Relapsing polychondritis (RP) is a rare systemic inflammatory disease characterized by recurrent inflammation of cartilage including ears, nose, tracheobronchial tree, chest wall and joints. Less commonly, it can cause inflammation of eyes, vasculature, nervous system, skin and inner ear. The purpose of this study is to study the pathogenesis of RP.

Relapsing PolychondritisVasculitis

University of Pennsylvania100 participantsStarted Feb 2021

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC)

NCT04480840

A Phase 2a, multicenter, randomized, double-blind, dose-ranging, placebo-controlled, study to evaluate the safety, tolerability, and PK of PLN-74809 in participants with primary sclerosing cholangitis and suspected liver fibrosis

Primary Sclerosing Cholangitis

Pliant Therapeutics, Inc.121 participantsStarted Jul 2020

Pasadena, California, United States • Redwood City, California, United States • Sacramento, California, United States +57 more locations

Longitudinal Study for Relapsing Polychondritis

Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC)

Find Trials by Condition in Philadelphia

Abatacept for the Treatment of Giant Cell Arteritis

A Randomized Multicenter Study for Isolated Skin Vasculitis

Fast Track to Fertility

A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia

Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial

Short Course Radiotherapy

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

UPenn Observational Research Repository on Neurodegenerative Disease

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Talimogene Laherparepvec and Panitumumab for the Treatment of Locally Advanced or Metastatic Squamous Cell Carcinoma of the Skin

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD

ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

HKI-272 for HER2-Positive Breast Cancer and Brain Metastases

A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments

Safety and Preliminary Efficacy of BNT314 in Cancer Patients With Malignant Solid Tumors

Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML