Clinical Trials in Philadelphia

Showing 2861-2880 of 20,904 trials

Comparing Numbing Techniques in Mohs Micrographic Surgery

NCT07222241

This study seeks to determine whether adjunct regional nerve blocks reduce pain and anxiety in adult patients undergoing Mohs micrographic surgery for face and scalp skin cancers. Participants will be randomized to one of two arms: (1) placebo regional nerve block with sterile normal saline or (2) adjunct regional nerve block with lidocaine. All patients receive local infiltration with lidocaine for complete anesthesia.

Skin Cancer FaceSkin Cancer Scalp

Abramson Cancer Center at Penn Medicine150 participantsStarted Jan 2026

Philadelphia, Pennsylvania, United States

Active Not RecruitingNA< 1 mile

TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients

NCT01918683

This trial is designed to be the initial prospective pilot investigation of the effectiveness of combined SBRT and TACE as bridging therapy for HCC patients awaiting liver transplanation. No prospective clinical trials regarding the combination of TACE and SBRT in pre-transplant population have been performed. We propose the trial be conducted as a pilot clinical trial with the goal of enrolling 40 patients into each arm

Hepatocellular Carcinoma

Abramson Cancer Center at Penn Medicine40 participantsStarted Jul 2013

Maywood, Illinois, United States • Portland, Oregon, United States • Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2/3< 1 mile

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

NCT05721573

A Phase II/III Randomized, Double-blind, Placebo-controlled, Multicenter Study to Determine the Efficacy and Safety of ABC008 in the Treatment of Subjects with Inclusion Body Myositis

Inclusion Body Myositis

Abcuro, Inc.272 participantsStarted Feb 2023

Phoenix, Arizona, United States • Irvine, California, United States • Los Angeles, California, United States +42 more locations

Comparing Numbing Techniques in Mohs Micrographic Surgery

TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

Find Trials by Condition in Philadelphia

Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Ibrutinib With Rituximab and Lenalidomide for Patients With Recurrent/Refractory Primary or Secondary Central Nervous System Lymphoma (PCNSL/SCNSL)

A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

OsteoPorotic fracTure preventION System (OPTIONS) Research Study

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

A Study With CIT-013 in HS Patients