Clinical Trials in Philadelphia

Showing 2621-2640 of 9,968 trials

Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis

NCT04713475

PBGM01 is a gene therapy for GM1 gangliosidosis intended to deliver a functional copy of the GLB1 gene to the brain and peripheral tissues. This study will assess in a 2 part design the safety, tolerability and efficacy of PBGM01 in patients with early onset infantile (Type 1) and late onset infantile (Type 2a) GM1 gangliosidosis

GM1 GangliosidosisGM1 Gangliosidosis, Type IGM1 Gangliosidosis, Type 2+1 more

Gemma Biotherapeutics26 participantsStarted Mar 2021

Oakland, California, United States • Minneapolis, Minnesota, United States • New Brunswick, New Jersey, United States +4 more locations

RECRUITING< 1 mile

Parkinson's Foundation PD GENEration Genetic Registry

NCT04994015

Development of a central repository for PD-related genomic data for future research.

Parkinson's Disease

Parkinson's Foundation25,000 participantsStarted Dec 2020

Birmingham, Alabama, United States • Chandler, Arizona, United States • Phoenix, Arizona, United States +53 more locations

Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis

Parkinson's Foundation PD GENEration Genetic Registry

Find Trials by Condition in Philadelphia

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Low-Carbohydrate Normocaloric Diet in Patients With Head and Neck Carcinoma (HNC)

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

StimRouter Registry Clinical Protocol

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

Clinical Trial of Approaches to Prostate Cancer Surgery

An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation

A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

BCMA-directed CAR-T Cell Therapy in Adult Patients With Multiple Myeloma

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

RecruitmEnt Assessed by eleCtRical Impedance Tomography