Clinical Trials in Philadelphia

Showing 2141-2160 of 20,904 trials

ACT With CF Self-Help Toolkit

NCT07436351

Acceptance and Commitment Therapy (ACT) tailored to meet the needs of adults living with cystic fibrosis (ACT with CF) is a newer form of talk therapy that has been shown to reduce anxiety \& depression and improve psychological flexibility, and value-based living. The investigators are now trying to find out whether a self-help version of this treatment (ACT with CF - Self Help Toolkit) is also effective in reducing anxiety and depression and improving psychological flexibility and value-based living in adults with CF. Adults with cystic fibrosis are at increased risk for anxiety and depression. This study examines whether a patient-facing therapy, ACT with CF - Self Help Toolkit can help to reduce anxiety and depression among adults with CF. This treatment can be accessed on the participant's smartphone.

Cystic Fibrosis (CF)Depressive and Anxiety DisordersPsychological Flexibility

Thomas Jefferson University60 participantsStarted Jan 2026

Philadelphia, Pennsylvania, United States

Enrolling By Invitation< 1 mile

An Observational Study of Patients With Chronic Liver Disease

NCT05744713

TARGET-Liver Disease (TARGET-LD) is an observational research study to conduct a comprehensive review of outcomes for patients with chronic liver disease (CLD).

Chronic Liver DiseaseCirrhosis

Target PharmaSolutions, Inc.500,000 participantsStarted Feb 2024

Los Angeles, California, United States • Redwood City, California, United States • Washington D.C., District of Columbia, United States +7 more locations

ACT With CF Self-Help Toolkit

An Observational Study of Patients With Chronic Liver Disease

Find Trials by Condition in Philadelphia

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM

Conduction System Pacing International Registry (CONSPIRE)

Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT

Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009)

Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide

Optical Diagnosis Versus Laser Measurement of Polyps' Size During Colonoscopy and Implications for Surveillance

Double-J PLUS Postmarket Registry Study

A Study of Alpelisib and Fulvestrant to Treat Endometrial Cancer

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

First-in-Human Study of ADCE-B05 in Patients With Advanced Solid Tumors

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)