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SIMPRO Research Center: Integration and Implementation of PROs for Symptom Management in Oncology Practice
Deficits in the management of common symptoms cause substantial morbidity for cancer patients.Because the health care delivery system is structured to be reactive and not proactive, there are missed opportunities to optimize symptom control. Growth in Internet access and proliferation of smartphones has created an opportunity to re-engineer cancer care delivery. Electronic symptom tracking and feedback is a promising strategy to improve symptom control. Electronic patient reported outcome (ePRO) monitoring of cancer symptoms has been shown to decrease symptom burden, improve quality of life, reduce acute care and even extend survival. SIMPRO will use functioning ePRO prototypes to create and refine the electronic symptom management system eSyM
A multi-disciplinary team of investigators from 6 health systems have formed the Symptom Management IMplementation of Patient Reported Outcomes in Oncology (SIMPRO) Research Center. SIMPRO will use functioning ePRO prototypes to create and refine the electronic symptom management system eSyM. eSyM is the name of the platform the team will refine, integrate, implement and evaluate. eSyM addresses each of the 4 evidence gaps by: * Implementing eSyM in cancer centers in small, rural or community-based systems. * Integrating eSyM into the EHR (electronic health record) of the predominant vendor used nationwide. * Leveraging evidence-based tools, patient engagement, and population management. * Executing this work using the Consolidated Framework for Implementation Research across all phases to maximize the chances that eSyM and similar systems achieve their intended goals and decrease the morbidity of cancer treatment at a population level. This project contains 5 activities: 1. Obtain stakeholder feedback 2. Build and deploy eSyM 3. Pilot test eSyM 4. Pragmatic stepped-wedge cluster randomized trial 5. Integration of eSyM data to develop algorithms to estimate the risk of experiencing an outcome, including, but not limited to, ED usage and hospitalization among cancer patients
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Maine Medical Center
Portland, Maine, United States
Dana Farber Cancer Institute
Boston, Massachusetts, United States
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
Brown University Health (formerly Lifespan Cancer Institute)
Providence, Rhode Island, United States
Baptist Memoiral HealthCare
Memphis, Tennessee, United States
West Virginia University Medical Center
Morgantown, West Virginia, United States
Start Date
July 25, 2019
Primary Completion Date
March 31, 2023
Completion Date
June 9, 2025
Last Updated
August 27, 2025
42,808
ACTUAL participants
Stakeholder Survey (Control Period)
OTHER
Stakeholder Survey (Intervention Period)
OTHER
Qualitative Interview
OTHER
SASS Questionnaire
OTHER
eSyM
OTHER
Lead Sponsor
Dana-Farber Cancer Institute
Collaborators
NCT04674267
NCT06596694
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT06445062