Clinical Trials in Philadelphia

Showing 20081-20100 of 20,904 trials

Project COPE:Managing Dementia at Home

NCT00259454

This study tests the effectiveness of an in-home intervention to reduce upset and burden among family caregivers, and decrease nursing home placement. The main hypothesis that will be tested is that compared to control group, subjects, experimental group participants will have enhanced well-being and fewer nursing home placements.

Dementia, Alzheimer Type

Thomas Jefferson University278 participantsStarted Jun 2005

Philadelphia, Pennsylvania, United States

COMPLETEDEARLY Phase 1< 1 mile

An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037

NCT00884520

Phase: Exploratory Study Objectives: To collect drug bio-distribution data, begin collection of baseline and tumor/background imaging data, acquire experience to improve study design and the conduct of future studies Design: Exploratory, open label, nonrandomized, multi-center study Duration: Three visits - one screening, one imaging, and one follow-up visit at 24 hours post-dose Procedures: Informed consent, collection of demographic information and medical history, physical examinations, vital signs, 12-lead ECGs, routine blood tests to assess major organ functions, complete blood counts and clinical chemistries for safety, blood sample for CA-IX assay, pre-dose and post-dose blood samples for metabolite analysis, dosing with \[F-18\]VM4-037, PET imaging scan, dosimetry estimation (normals), urine collections (normals), tumor immunohistochemistry with CA-IX biomarker, follow up to imaging to collect adverse events Subjects: Approximately sixteen (16) adult subjects including four (4) healthy volunteers and twelve (12) cancer subjects who have confirmed or highly suspected diagnosis of head \& neck, lung, large solitary hepatic and renal cell cancer, as defined by protocol criteria

Lung CancerSquamous Cell CarcinomaHead and Neck Cancer+2 more

Siemens Molecular Imaging16 participantsStarted Apr 2009

Philadelphia, Pennsylvania, United States

Project COPE:Managing Dementia at Home

An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037

Find Trials by Condition in Philadelphia

Rasagiline in Advanced Parkinson's Disease Patients With Motor Fluctuations Treated With Levodopa/Carbidopa Therapy.

ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH)

Study of BMS-587101 in Patients With Moderate to Severe Psoriasis

AZD8683 Single Ascending Dose Study

Glucocorticoid-induced Osteopenia in Children

Diabetes Control and Complications Trial (DCCT)

Black Cohosh as Alternative Therapy for Treating Menopause-Related Anxiety

The Effect of Nexium on Transmucosal Esophageal Leak

A Phase I Study of BMS-275183 (Oral Taxane) Given on a Daily Schedule in Combination With Esomeprazole (Nexium) in Patients With Advanced Cancer

Multicenter Study of Rasagiline in Parkinson's Disease Patients Using Levodopa and Experiencing Motor Fluctuations

Safety and Efficacy of Avonex in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Study of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

Bryostatin 1 and Cytarabine in Treating Patients With Relapsed Acute Myelogenous Leukemia

A Randomized, Placebo-Controlled Trial of BMS-275291 Given Daily for 12 Months to Women With Stage 1c-IIIA Breast Cancer Receiving Adjuvant Chemotherapy and/or Hormonal Therapy

A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis

Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiforme

Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background

A Phase I Study of BMS-275183 Given on a Daily Schedule in Patients With Advanced Malignancies