Clinical Trials in Pennsylvania

Showing 1901-1920 of 19,675 trials

Nurse AMIE (Addressing Malignancies in Individuals Everyday)

NCT05221606

Nurse AMIE 3.0 is testing the effectiveness of an electronic symptom management system on overall survival in people with stage 3 and 4 cancer who live in rural areas.

Cancer

University of Pittsburgh344 participantsStarted May 2022

Butler, Pennsylvania, United States • Greenville, Pennsylvania, United States • Hershey, Pennsylvania, United States +5 more locations

COMPLETEDPhase 336 miles

Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis

NCT05945615

After an episode of facial paralysis, as nerves recover, they aberrantly regenerate and send additional branches to the incorrect muscles in addition to the intended muscle. This leads to what is known as Aberrant Regeneration Syndrome, Post-paralysis Synkinesis, or Nonflaccid Facial Paralysis. It is characterized by poor facial symmetry and function, hypertonic facial muscles at rest, and abnormal facial movements. One sequela is acquired blepharoptosis causing a smaller ocular aperture, visual field obstruction, cosmetic deformity, and abnormal periocular spasms. This study aims to evaluate an FDA approved medication for acquired blepharoptosis due to synkinesis/hyperkinesis as an adjunct to treatment.

BlepharoptosisSynkinesisHyperkinesis+1 more

Milton S. Hershey Medical Center36 participantsStarted Jan 2024

Hershey, Pennsylvania, United States

Nurse AMIE (Addressing Malignancies in Individuals Everyday)

Oxymetazoline Drops for Acquired Blepharoptosis From Synkinesis

Find Trials by Condition in Pennsylvania

Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome

Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients

A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)

Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Type 1 Diabetes Extension Study

A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy

IBI363 vs Docetaxel in Patients With Advanced Squamous Lung Cancer After Standard Treatments Have Failed