Clinical Trials in Pennsylvania

Showing 11461-11480 of 16,895 trials

Cohort B of the Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter

NCT03719014

A Prospective, Multi-Center, Non-randomized, Single arm, Open label, Supplemental Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter in Facilitating Crossing Chronic Total Occlusion (CTO) Coronary Lesions

Coronary Occlusion

Nitiloop Ltd.60 participantsStarted Nov 2018

Little Rock, Arkansas, United States • New York, New York, United States • York, Pennsylvania, United States

TERMINATEDPhase 253 miles

The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From Chemotherapy Treatment

NCT01655823

Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect of many chemotherapeutic agents including vincristine, paclitaxel, cisplatin, oxaliplatin, bortezomib and ixabepilone. Chemotherapy-induced peripheral neuropathy commonly occurs in greater than 40% of patients. To improve the peripheral neuropathy, the chemotherapy dosing is often either decreased or discontinued potentially affecting tumor responsiveness, prognosis, and survival. There is an unmet medical need for treatment of cancer patients with chemotherapy induced neuropathic pain (CINP) and the proposed study will investigate the efficacy and safety of multiple dose levels of tetrodotoxin (TTX) versus placebo in moderate to severe neuropathic pain caused by chemotherapy.

PainPeripheral NeuropathyNeuropathic Pain

Wex Pharmaceuticals Inc.125 participantsStarted Jul 2012

Fountain Valley, California, United States • Fountain Valley, California, United States • Laguna Hills, California, United States +20 more locations

Cohort B of the Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter

The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From Chemotherapy Treatment

Find Trials by Condition in Pennsylvania

Phase I Study Of The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of PF-04236921 In Patients With Rheumatoid Arthritis

Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis

Study to Evaluate the Efficacy and Safety of Suptavumab (REGN2222) for the Prevention of Medically Attended RSV (Respiratory Syncytial Virus) Infection in Preterm Infants

HORIZANT (Gabapentin Enacarbil Extended-Release Tablets) for the Treatment of Alcohol Use Disorder

Safety and Efficacy Study of Ulocuplumab and Nivolumab in Subjects With Solid Tumors

Lenalidomide/Bortezomib/Dexamethasone for Multiple Myeloma (MM)

Eplerenone for the Treatment of Central Serous Chorioretinopathy

Safety and Efficacy of Cariprazine in Schizophrenia

CONSISTENT 1: Metabolic and Safety Outcomes of Hylenex Recombinant (Hyaluronidase Human Injection) Preadministered at CSII Infusion Site in Participants With Type 1 Diabetes Mellitus (T1DM)

A Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease

Safety Evaluation of the ReWalk ReStore Device in Subjects With Mobility Impairments Due to Stroke

A Study of Enzastaurin in Participants With Follicular Lymphoma

Phase IIIB Study Evaluating the Effects of Atazanavir Powder With Ritonavir in HIV-infected Pediatric Patients

Safety and Tolerability Study of MEDI-551, a B-cell Depleting Agent, to Treat Relapsing Forms of Multiple Sclerosis

Safety Evaluation of 3K3A-APC in Ischemic Stroke

Global Non-interventional Heart Failure Disease Registry

Study to Assess Functionality, Reliability, and Performance of a Single-Use Auto-Injector With Benralizumab Administered at Home

Combination Study of Deferasirox and Erythropoietin in Patients With Low- and Int-1-risk Myelodysplastic Syndrome.