Clinical Trials in Pennsylvania

Showing 9421-9440 of 14,950 trials

Using an End-of-life Conversation Game to Engage Underserved Communities in Advance Care Planning

NCT03456921

This national project will provide an effective, evidence-based intervention for advance care planning (ACP) to 50 underserved US communities, those with poor access to healthcare systems due to economic, cultural or other barriers. The project will also examine 15 of the 50 communities to learn about the unique needs of African American communities in regards to ACP and to assess the intervention with this population. The team includes the Hospice Foundation of America and a university-based research team from Penn State Milton S. Hershey Medical Center.

Advance Care PlanningVulnerable PopulationsAdvance Directives+1 more

Milton S. Hershey Medical Center1,122 participantsStarted Feb 2018

Hershey, Pennsylvania, United States

COMPLETEDPhase 440 miles

World-wide Randomized Antibiotic Envelope Infection Prevention Trial

NCT02277990

Medtronic , Inc. is sponsoring the World-wide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT), a randomized, prospective, multi-center, single blinded, post-market, interventional clinical study. This study will evaluate the ability of the TYRX™ envelope to reduce major Cardiac Implantable Electronic Device (CIED) infections through 12-months post-procedure following CIED generator replacement, upgrade, revision, or de novo cardiac resynchronization therapy defibrillator (CRT-D) implant. Additionally, this large device study provides the unique opportunity to prospectively characterize the performance of Medtronic's lead monitoring features in subjects whose CIED system includes a transvenous right ventricular (RV) defibrillation lead. Finally, the WRAP-IT study will serve as a post-approval study for those geographies requiring a post-approval study of the TYRX™ envelope.

CIED Related Infection

Medtronic Cardiac Rhythm and Heart Failure7,075 participantsStarted Jan 2015

Anchorage, Alaska, United States • Mesa, Arizona, United States • Scottsdale, Arizona, United States +178 more locations

Using an End-of-life Conversation Game to Engage Underserved Communities in Advance Care Planning

World-wide Randomized Antibiotic Envelope Infection Prevention Trial

Find Trials by Condition in Pennsylvania

19 Versus 22-Gauge Needle for EUS-LB

Trial of Lithium Carbonate for Treatment of Osteoporosis-pseudoglioma Syndrome

A Long-Term Efficacy and Safety Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis

AMR PH GL 2007 CL001 Phase 3 Trial in Patients With Small Cell Lung Cancer After Failure of First-Line Chemotherapy

Feasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients

Safety, Pharmacokinetics, and Pharmacodynamics of Oral Azacitidine in Subjects With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia and Acute Myelogenous Leukemia

Lapatinib and Trastuzumab With or Without Endocrine Therapy

A 38 Week Trial Comparing Effect and Safety of Insulin Degludec/Insulin Aspart vs. Insulin Glargine Plus Insulin Aspart in Subjects With Type 2 Diabetes Treated With Basal Insulin With or Without Oral Antidiabetic Treatment in Need of Treatment Intensification

Study to Evaluate the Safety and Efficacy of Topical Minocycline Gel in Patients With Papulopustular Rosacea

Microbiota Restoration Therapy for Recurrent Clostridium Difficile-associated Diarrhea

Evaluating the Safety and Efficacy of Anti-Influenza Intravenous Hyperimmune Immunoglobulin (IVIG) in Adults Hospitalized With Influenza

Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)

POSITIVE Stroke Clinical Trial

An Open Label Extension Study of the Safety and Clinical Utility of IPX066 in Subjects With Parkinson's Disease

Study Evaluating Two Dose Levels of Targretin Capsules in Participants With Refractory Cutaneous T-Cell Lymphoma (CTCL)

Study of Debio 1450 for Bacterial Skin Infections

Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer

Study in Subjects With Moderate Atopic Dermatitis