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Clinical Trials in Ohio | 20,938 Studies Near You | Clareo Health

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Clinical Trials in Ohio

Discover 20,938 clinical trials near Ohio. Find research studies in your area.

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Showing 19581-19600 of 20,938 trials

COMPLETEDPhase 327 miles

Efficacy of Ramelteon on Transient Insomnia in Healthy Adults

NCT00671398

The purpose of this study is to evaluate the safety and efficacy of Ramelteon, once daily (QD), in healthy subjects within a sleep lab.

Transient Insomnia

Takeda289 participantsStarted Dec 2002

Palm Springs, California, United States • San Diego, California, United States • Miami, Florida, United States +9 more locations

COMPLETEDPhase 327 miles

Efficacy of Ramelteon in Subjects With Chronic Insomnia

NCT00671086

The purpose of this study is to determine the long-term safety of Ramelteon, once daily (QD), in subjects with chronic insomnia.

Sleep Initiation and Maintenance Disorders

Takeda1,213 participantsStarted Feb 2003

Birmingham, Alabama, United States • Mobile, Alabama, United States • Phoenix, Arizona, United States +119 more locations

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Data from ClinicalTrials.govTerms

COMPLETEDPhase 227 miles

Safety and Efficacy of Ramelteon in Healthy Subjects

NCT00671190

The purpose of this study is to determine the phase-advance in circadian rhythms in healthy adults subjects taking ramelteon, once daily (QD).

Takeda75 participantsStarted Mar 2005

Hot Springs, Arkansas, United States • Los Angeles, California, United States • San Diego, California, United States +10 more locations

COMPLETEDPhase 332 miles

Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia

NCT00331487

Efficacy comparison of Pioglitazone, once daily (QD), to Rosiglitazone in participants with Type 2 Diabetes

Diabetes Mellitus

Takeda719 participantsStarted Sep 2000

Anniston, Alabama, United States • Birmingham, Alabama, United States • Tucson, Arizona, United States +64 more locations

COMPLETEDPhase 332 miles

Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis Who Participated in the MS-F204 Trial

NCT00649792

The purpose of the study is to evaluate the safety, tolerability and activity of Fampridine-SR when administered for up to 36 additional months in patients who previously participated in the MS-F204 study or until it becomes commercially available, whichever comes first.

Multiple Sclerosis

Acorda Therapeutics214 participantsStarted Aug 2007

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Fayetteville, Arkansas, United States +39 more locations

COMPLETEDPhase 332 miles

Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

NCT00124982

The purpose of this study is to summarize the safety and tolerability of abatacept during 6 months of combined treatment with one or more of the background non-biologic disease modifying anti-rheumatic drugs (DMARDs) approved for rheumatoid arthritis (RA) in subjects with active RA. Secondary objectives assessed the clinical efficacy of combination treatment, including disease activity, physical function, and quality of life outcomes.

Rheumatoid Arthritis

Bristol-Myers Squibb1,286 participantsStarted Apr 2005

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Paradise Valley, Arizona, United States +145 more locations

COMPLETEDPhase 332 miles

Study of Levalbuterol and Racemic Albuterol in Pediatric Subjects With Reactive Airways Disease (RAD)

NCT00685126

The purpose of this study is to compare the efficacy of two dose levels of levalbuterol compared with one dose level of racemic albuterol in pediatric subjects aged birth to 48 months old.

Reactive Airways Disease (RAD)

Sumitomo Pharma America, Inc.117 participantsStarted Feb 2001

Little Rock, Arkansas, United States • Corona, California, United States • Englewood, California, United States +31 more locations

TERMINATED32 miles

Long Term Follow-Up Study for rAAV-GAD Treated Subjects

NCT01301573

The purpose of this observational study is the long term follow-up of Parkinson's patients who participated in a clinical trial in which they received AAV-GAD gene transfer into the subthalamic nucleus (STN) region of the brain. Patients will be followed once a year for up to five (5) years. The study will monitor and evaluate the long term effects of AAV-GAD and provide long term safety information.

Parkinson's Disease

Neurologix, Inc.40 participantsStarted Jan 2011

Stanford, California, United States • Aurora, Colorado, United States • Boston, Massachusetts, United States +3 more locations

COMPLETEDPhase 332 miles

Study of Gabapentin Extended Release (G-ER)in the Treatment of Vasomotor (Hot Flashes/Hot Flushes) Symptoms in Postmenopausal Women.

NCT00777023

Depomed's Gabapentin Extended Release is an investigational, extended release formulation of gabapentin that is being studied for the treatment of hot flashes in postmenopausal women

Depomed565 participantsStarted Oct 2008

Birmingham, Alabama, United States • Chandler, Arizona, United States • Scottsdale, Arizona, United States +42 more locations

COMPLETEDPhase 332 miles

6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia

NCT00352144

To evaluate the long-term efficacy of eszopiclone administered for up to 6 months in subjects with primary insomnia on subjective sleep measures, compared to placebo.

Primary Insomnia

Sumitomo Pharma America, Inc.830 participantsStarted Oct 2003

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Phoenix, Arizona, United States +55 more locations

COMPLETEDPhase 295 miles

An Efficacy Study of Compound LY2624803 in the Treatment of Patients With Chronic Insomnia

NCT00784875

The purpose of this study is to compare an investigational drug (LY2624803) with placebo and with zolpidem in the treatment of outpatients with chronic insomnia.

Primary InsomniaSecondary Insomnia

Eli Lilly and Company643 participantsStarted Oct 2008

Birmingham, Alabama, United States • Glendale, Arizona, United States • Mesa, Arizona, United States +46 more locations

COMPLETEDPhase 397 miles

Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.

NCT00671294

This purpose of this study is to assess the efficacy and safety of Ramelteon, once daily (QD), in elderly subjects with chronic insomnia.

Chronic Insomnia

Takeda100 participantsStarted Oct 2002

Hot Springs, Arkansas, United States • Irvine, California, United States • Palm Springs, California, United States +15 more locations

COMPLETEDPhase 3127 miles

Study of Levalbuterol, Racemic Albuterol and Placebo in Subjects Twelve Years of Age and Older With Asthma

NCT00073840

The primary objective of this study is to investigate the efficacy of levalbuterol 90 ug (2 actuations, 45 ug each) versus placebo (2 actuations) in the treatment and prevention of bronchoconstriction in adolescent and adult subjects with asthma, with all treatments administered 4 times a day (QID).

Sumitomo Pharma America, Inc.386 participantsStarted Dec 2002

Oxford, Alabama, United States • Tucson, Arizona, United States • Corona, California, United States +51 more locations

COMPLETEDPhase 3135 miles

A Study of TNFerade™ Biologic With 5-FU and Radiation Therapy for First-Line Treatment of Unresectable Locally Advanced Pancreatic Cancer

NCT00051467

The primary purpose of this study is to assess the safety and effectiveness of TNFerade™ Biologic when administered concurrently with 5-FU and radiation therapy as first-line treatment of unresectable locally advanced pancreatic cancer. TNFerade™ is a replication deficient adenovirus vector containing the gene for TNF-alpha controlled by a chemoradiation inducible promoter. This allows the expression of TNF-alpha to be greatest in the area receiving radiation. TNF-alpha is a cytokine that has been shown to have potent anti-cancer activities but, due to systemic toxicity, could not be delivered at effective doses. TNFerade™ Biologic is a novel way of selective delivery of TNF-alpha to tumor cells. TNFerade™ Biologic will be injected during five weekly injection sessions, concomitant with radiation and 5-FU. TNFerade™ Biologic will be administered by direct intratumoral injection using a percutaneous approach (PTA) or endoscopic ultrasound (EUS).

Pancreatic Cancer

La Jolla, California, United States • Los Angeles, California, United States • Orange, California, United States +22 more locations

COMPLETEDPhase 4146 miles

Costs & Outcomes of Hospitalization/Treatment With Levalbuterol & Albuterol in Asthma or Chronic Obstructive Pulmonary Disease (COPD) Subjects

NCT00667797

An analysis of the costs and outcomes associated with hospitalization and treatment of Levalbuterol versus Racemic Albuterol in subjects with Asthma and COPD.

Sumitomo Pharma America, Inc.486 participantsStarted Mar 2003

Birmingham, Alabama, United States • Chula Vista, California, United States • Oakland, California, United States +15 more locations

COMPLETEDPhase 3158 miles

Reliability of a Top Mount Actuation Indicator With Levalbuterol MDI in Adult and Pediatric Subjects With Asthma or COPD

NCT00583986

This is a study to investigate the reliability, ruggedness and safety of the top mounted actuation indicator (TMAI) when used with Levalbuterol HFA MDI.

AsthmaChronic Obstructive Pulmonary DiseaseCOPD

Sumitomo Pharma America, Inc.150 participantsStarted Sep 2005

Encinatas, California, United States • Huntington Beach, California, United States • Mesa, California, United States +23 more locations

COMPLETEDPhase 2379 miles

Study of Arformoterol Tartrate Inhalation Solution and Racemic Formoterol in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

NCT00685529

The purpose of this study is to compare the blood levels of arformoterol tartrate inhalation solution to racemic formoterol in male and female subjects with mild to moderate Chronic Obstructive Pulmonary Disease (COPD).

Sumitomo Pharma America, Inc.24 participantsStarted Apr 2005

Long Beach, California, United States • Fort Lauderdale, Florida, United States • Raleigh, North Carolina, United States +3 more locations

COMPLETEDPhase 2414 miles

A Safety and Tolerability Study of Levalbuterol HFA Metered Dose Inhaler in Subjects With Asthma

NCT00684827

The purpose of this study is to compare the safety and tolerability of levalbuterol HFA metered dose inhaler (MDI) versus racemic albuterol HFA MDI.

Sumitomo Pharma America, Inc.32 participantsStarted Oct 2002

Encinitas, California, United States • Los Angeles, California, United States • North Dartmouth, Massachusetts, United States +1 more locations

COMPLETEDPhase 2414 miles

Safety and Tolerability Study of Levalbuterol HFA Compared to Racemic Albuterol HFA in Subjects With Asthma

NCT00685022

The purpose of this study is to compare the safety and tolerability of levalbuterol HFA metered dose inhaler (MDI) versus racemic albuterol HFA MDI.

Sumitomo Pharma America, Inc.49 participantsStarted Jun 2003

Encinitas, California, United States • North Dartmouth, Massachusetts, United States • St Louis, Missouri, United States

COMPLETEDPhase 4460 miles

Safety of Ramelteon in Elderly Subjects

NCT00568789

The purpose of this study is to investigate the effects of ramelteon in elderly subjects on balance, mobility and memory impairment after awakening in the middle of the night following bedtime dosing.

Takeda33 participantsStarted Jun 2006

Costa Mesa, California, United States • San Diego, California, United States • Miami, Florida, United States +3 more locations

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