Clinical Trials in Ohio

Showing 5161-5180 of 15,929 trials

Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers

NCT06053463

To explore the wear experience in Dailies TOTAL1 Multifocal contact lenses in presbyopic adults who have previously dropped out of contact lens wear.

Presbyopia

Jennifer Fogt35 participantsStarted Oct 2023

Columbus, Ohio, United States • Granville, Ohio, United States

RECRUITING32 miles

IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry

NCT03536897

This is a prospective, registry trial which will enroll women aged 65 and above with early stage, low risk breast cancer who will be treated with partial mastectomy and intraoperative radiation therapy (IORT). The primary aim is to determine the 5-year risk of in-breast tumor recurrence. Secondary aims include identification of acute- and late-toxicity, cosmetic result, disease-free survival and overall survival.

Breast Cancer

Mount Carmel Health System168 participantsStarted Feb 2018

Columbus, Ohio, United States

COMPLETEDPhase 232 miles

A Dose-ranging Study of the Efficacy of ESN364 in Postmenopausal Women Suffering Vasomotor Symptoms (Hot Flashes)

NCT03192176

This study determined the effects of different doses and dosing regimens of ESN364 on the frequency and severity of hot flashes. The treatment was administered for 12 weeks to postmenopausal women, aged 40 to 65, suffering at least 50 moderate to severe hot flashes per week.

MenopauseHot Flashes

Astellas Pharma Global Development, Inc.356 participantsStarted Jul 2017

Anniston, Alabama, United States • Birmingham, Alabama, United States • Phoenix, Arizona, United States +48 more locations

Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers

IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry

A Dose-ranging Study of the Efficacy of ESN364 in Postmenopausal Women Suffering Vasomotor Symptoms (Hot Flashes)

Find Trials by Condition in Ohio

Trametinib in Treating Patients With Epithelioid Hemangioendothelioma That is Metastatic, Locally Advanced, or Cannot Be Removed by Surgery

Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)

Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

A Study of Abemaciclib (LY2835219) in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer

A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

First in Human Study of M1069 in Advanced Solid Tumors

RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)

PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)

Durvalumab And Radiation Therapy Followed by Adjuvant Durvalumab in Patients With Urothelial Cancer (T2-4 N0-2 M0) of the Bladder

A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

A Study of ZN-c3 in Patients With Ovarian Cancer

Feasibility Study of the Reia Vaginal Pessary

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

A Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS)