Clinical Trials in North Carolina

Showing 8101-8120 of 15,496 trials

Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression

NCT00066859

RATIONALE: Antidepressants such as sertraline and the herb hypericum perforatum (St. John's wort) may be effective in treating mild to moderate depression. It is not yet known which treatment is more effective in improving depression in patients who have cancer. PURPOSE: This randomized phase III trial is studying how well sertraline works compared to St. John's wort in treating mild to moderate depression in patients with solid tumors.

DepressionUnspecified Adult Solid Tumor, Protocol Specific

Wake Forest University Health Sciences2 participantsStarted Mar 2004

Oakland, California, United States • Rome, Georgia, United States • Decatur, Illinois, United States +3 more locations

COMPLETEDPhase 325 miles

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

NCT00070148

RATIONALE: Oxandrolone and megestrol may help prevent weight loss and improve quality of life in patients with cancer. It is not yet known whether oxandrolone is more effective than megestrol in preventing weight loss and improving quality of life in patients who are receiving chemotherapy for solid tumors. PURPOSE: This randomized phase III trial is studying oxandrolone to see how well it works compared to megestrol in preventing weight loss and improving quality of life in patients who are receiving chemotherapy for solid tumors.

Unspecified Adult Solid Tumor, Protocol SpecificWeight Changes

Wake Forest University Health Sciences155 participantsStarted Mar 2004

Newark, Delaware, United States • Miami Beach, Florida, United States • Louisville, Kentucky, United States +17 more locations

Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

Find Trials by Condition in North Carolina

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Combination Chemotherapy Plus Thalidomide in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Study to Evaluate Switching From a Regimen of Two Nucleos(t)Ide Reverse Transcriptase Inhibitors (NRTI) Plus a Third Agent to a Fixed Dose Combination (FDC) of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF), in Virologically-Suppressed, HIV-1 Infected African American Participants

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)

A Safety and Efficacy Comparison of BLI4700 Bowel Preparation Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy

OptiMesh® for Lumbar Interbody Fusion Trial (OLIF)

A Study Evaluating Pertuzumab (Perjeta) Combined With Trastuzumab (Herceptin) and Standard Anthracycline-based Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced, Inflammatory, or Early-stage Breast Cancer

Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite

Stress Management for Cancer Patients: How Well Does it Work? (C2H-D)

A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, or Hepatocellular Carcinoma

Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery

First in Human Study for Safety and Tolerability of AL003.

A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors

An Extension Study to Assess the Long-Term Safety and Efficacy of Pasireotide in Participants With Acromegaly

A Comparative Study of BAT1706 and EU Avastin® in Patients With Advanced Non Squamous Non Small Cell Lung Cancer

Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)