Clinical Trials in North Carolina

Showing 5361-5380 of 20,428 trials

A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1

NCT06462404

The primary purpose of this study is to evaluate the efficacy of single oral doses of E2086 compared to placebo in the treatment of excessive daytime sleepiness (EDS) as assessed by the Maintenance of Wakefulness Test (MWT) in adult participants with narcolepsy type 1 (NT1).

Narcolepsy Type 1 (NT1)

Eisai Inc.22 participantsStarted Jun 2024

Santa Ana, California, United States • Miami, Florida, United States • Macon, Georgia, United States +11 more locations

RECRUITING41 miles

Reliability of Pupil Response to Acute Pain

NCT02628314

The purpose of this research study is to test whether researchers can reliably measure the response pupils have when an acute painful stimulus is experienced. Changes in the size of the pupil of the eye can be an indicator of brain activity in a region of the brain that is important for feeling pain.

PainOsteoarthritis

Wake Forest University Health Sciences80 participantsStarted Aug 2015

Winston-Salem, North Carolina, United States

A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1

Reliability of Pupil Response to Acute Pain

Find Trials by Condition in North Carolina

A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (Core OLE)

Psychotherapy Feasibility Pilot of the Carolina Recovery From Depression Protocol

Infant Formula in Infants and Children With Cow's Milk Allergy

Study of Airway Inflammatory Responses to Experimental Rhinovirus Infection

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

Sling vs Botox for Mixed Incontinence

Efficacy and Safety of GMRx2 Compared to Dual Combinations for the Treatment of Hypertension

Study of the Relay Pro® Thoracic Stent-Graft in Subjects With Traumatic Injury of the Descending Thoracic Aorta

Efficacy and Safety of GMRx2 Compared to Placebo for the Treatment of Hypertension

A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin

Evaluation of the Safety and Efficacy of Ang-(1-7) to Enhance Cognitive Function in Participants Undergoing CABG

RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD

Multicenter Trial of Meditation and Health Education for Cardiometabolic Disease in Black Women

Study to Assess the Safety, Tolerability, Pharmacokinetics and Immunogenicity of AK006 in Healthy Subjects and Subjects With Chronic Spontaneous Urticaria

Prostate Oncologic Therapy While Ensuring Neurovascular Conservation (POTEN-C)

Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy

A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

Sulindac and Breast Density in Women at Risk of Developing Breast Cancer