Efficacy and Safety of GMRx2 Compared to Placebo for the Treatment of Hypertension

TRIAL DRUG: GMRx2: single pill combination of telmisartan/amlodipine/indapamide Dose version 1: telmisartan 10 mg/amlodipine 1.25 mg/indapamide 0.625 mg Dose version 2: telmisartan 20 mg/amlodipine 2.5 mg/indapamide 1.25 mg INDICATION: Hypertension TRIAL TITLE: Efficacy and safety of GMRx2 compared to placebo for the treatment of hypertension. OBJECTIVES: To investigate the efficacy and safety of GMRx2 compared to placebo for the treatment of hypertension. INTERVENTION: A 2-week single-blind placebo run-in will be followed by a 4-week double-blind period with randomization to GMRx2 dose version 1, GMRx2 dose version 2 or placebo.