Clinical Trials in North Carolina

Showing 4461-4480 of 12,431 trials

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

NCT05383508

This is a single-center, randomized, controlled, open-label, cross-over study with healthy adult smokers. The study will investigate the nicotine pharmacokinetic (PK) profiles of two e-liquid variants used with the P4M3 Gen 2.0 e-cigarette, compared to smoking combustible cigarettes. In addition, pharmacodynamic (PD) effects (subjective effects and related behavioral assessments), will be evaluated to provide further insights on product evaluation, craving, liking, puffing topography. The study will be conducted with three periods and six sequences in a cross-over design. This study is exploratory and there is no pre-specified hypothesis to be tested.

Nicotine VapingNicotineVaping

Philip Morris Products S.A.36 participantsStarted Apr 2022

High Point, North Carolina, United States

COMPLETEDPhase 346 miles

A Study Evaluating JUVÉDERM® VOLUMA® XC Injectable Gel for Correction of Temple Hollowing in Adult Participants ≥ 22 Years Old

NCT04414397

The objectives of this study are to evaluate the safety and effectiveness of Juvederm® Voluma® XC injectable gel in adult participants seeking correction of temple hollowing

Temple Hollowing

Allergan205 participantsStarted May 2020

Los Angeles, California, United States • Newport Beach, California, United States • Boca Raton, Florida, United States +12 more locations

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

A Study Evaluating JUVÉDERM® VOLUMA® XC Injectable Gel for Correction of Temple Hollowing in Adult Participants ≥ 22 Years Old

Find Trials by Condition in North Carolina

Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)

Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

Study of an Anti-OX40 Monoclonal Antibody (KHK4083) in Subjects With Moderate to Severe Atopic Dermatitis

Safety and Immunogenicity of Pneumococcal Conjugate Formulations in Healthy Adults 18 Through 49 Years of Age

Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis

Automated Insulin Delivery for INpatients With DysGlycemia (AIDING) Feasibility

The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

Study of Mogamulizumab + MEDI4736 (Durvalumab) and Mogamulizumab + Tremelimumab in Subjects w/ Advanced Solid Tumors

Post Market Study of Parietene™ DS Composite Mesh in Ventral Hernia Repair

PRS-343 in HER2-Positive Solid Tumors

Ecopipam Treatment of Self-Injurious Behavior in Subjects With Lesch-Nyhan Disease

Management of Chronic Low Back Pain in Older Adults Using Auricular Point Acupressure

Ancora-SB Overtube Complete Positioning and Optical Visualization During Endoscopic Procedures

The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

A Study Of PF-04449913 In Select Hematologic Malignancies