Metabolic Effects of Perimenopause

Exclusion Criteria

• •Have current and/or history of cardiovascular disease, diabetes, metabolic, thyroid, pulmonary, renal, hepatic, gastrointestinal, musculoskeletal disorders or medical or surgical events, such as bariatric surgery, heart surgery, or any joint or musculoskeletal injuries or surgeries occurring in the 6-months prior to enrollment, that may significantly influence study outcomes or prevent safe participation.
• •Gained or lost \>5 kg in the previous 2 months
• •Have a self-identified or clinically diagnosed eating disorder
• •Undergone a full or partial hysterectomy for treatment of menopausal symptoms
• •Have uncontrolled hypertension or an abnormal electrocardiogram.
• •Have an ongoing diagnosed mental disorder with a change in medication in the previous 6 months.
• •Taking metabolism-altering drugs or medications outside of estrogen replacement therapy that may influence study outcomes (i.e. corticosteroids, stimulants, insulin, thyroid medications) or phytoestrogens.
• •Diagnosed with polycystic ovarian syndrome (PCOS).
• •Participating in more than 75 minutes per week of moderate exercise per week.
• •Currently pregnant or planning to become pregnant (determined from urine pregnancy test)
• •Currently nursing or have had a child within the previous 6 months
• •Has participated in another clinical trial within four weeks prior to enrollment that in the opinion of the PI would influence the results.
• •Has severely impaired hearing or speech or inability to speak English.
• •Unwilling or unable to comply with the study protocol, including abstaining from caffeine, tobacco, alcohol, and physical activity before testing days.