Clinical Trials in New York

Showing 4281-4300 of 22,668 trials

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT02199665

This phase I trial studies the side effects and best dose of selinexor and carfilzomib when given together with dexamethasone in treating patients with multiple myeloma that has returned or does not respond to treatment. Drugs used in chemotherapy, such as selinexor and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving selinexor, carfilzomib, and dexamethasone may be a better treatment for multiple myeloma.

Refractory Multiple Myeloma

University of Chicago52 participantsStarted Jun 2014

Scottsdale, Arizona, United States • Chicago, Illinois, United States • Ann Arbor, Michigan, United States +2 more locations

Active Not RecruitingPhase 3< 1 mile

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

NCT05680818

The primary purpose of the study is to understand the effectiveness, safety, and tolerability of encaleret when compared to standard of care (SoC) treatment in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1).

Autosomal Dominant Hypocalcemia (ADH)

Calcilytix Therapeutics, Inc., a BridgeBio company67 participantsStarted Jan 2023

Oakland, California, United States • Aurora, Colorado, United States • Indianapolis, Indiana, United States +22 more locations

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

Find Trials by Condition in New York

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

Enhanced Nutritional Optimization in LVAD Trial

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Efficacy of the I-CARE Digital Health Intervention

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With Cold Agglutinin Disease (CAD)

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Atherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol Balance

Studies of Brain and Body Interaction

Post-Market Study to Assess iTind Safety in Comparison to UroLift

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop

Multicenter Assessment of the Pancreas in Type 1 Diabetes

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease