ADAPT - A Patient Registry of the Real-world Use of Orenitram®

Inclusion Criteria

• •Patients are eligible for the registry if:
• •1. The patient voluntarily gives informed consent to participate in the study.
• •2. The patient must be at least 18 years of age or older.
• •3. The patient is prescribed Orenitram (per the package insert indication), and plans to initiate therapy with this medication or has been receiving Orenitram for 182 or fewer days.
• •4. The patient agrees to dosing, prostacyclin-related AE of interest record keeping, survey participation during designated time periods, and recording any medication changes, use, for the duration of the study.
• •5. The patient has the ability to answer surveys and use the diary in English.
• •6. The patient must have an email address and be willing to access the PRO Portal.