Clinical Trials in Nashville

Showing 881-900 of 9,711 trials

A Prospective Sub-Study of the Global Hypophosphatasia Registry

NCT05234567

In this prospective observational sub-study, participants with pediatric-onset hypophosphatasia (HPP) (perinatal/infantile- or juvenile-onset) of any age will be followed for a minimum of 5 years at sites in the United States and potentially 1 or 2 other countries.

Hypophosphatasia

Alexion Pharmaceuticals, Inc.30 participantsStarted Aug 2022

Hartford, Connecticut, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +9 more locations

RECRUITINGNA< 1 mile

Randomized Clinical Trial for Ewing Amputation in the VA

NCT05437562

This study follows the Pilot Investigation of Ewing Amputation for Veterans with PAD Undergoing a Below Knee Amputation. The 2 year pilot feasibility phase has concluded recruitment and enrollment. The current phase is a 5 year randomized study of Ewing Below Knee Amputation vs. Standard Below Knee Amputation. If Veterans participate, they will be randomized to either Ewing Amputation or Standard Below Knee Amputation. The scientific premise motivating this proposal is that Ewing Amputation is a promising surgical technique that may improve walking metrics in dysvascular Veterans by providing a better residual limb and improving pain and balance. In preparation of this proposal, we have formed multi-disciplinary surgical teams at each site, and we have been supported by a clinical trial planning meeting to garner the considerable expertise in rehabilitation and amputee assessment from VA and DOD experts to assist in the design of this proposal, testing the overall hypothesis that: Ewing Amputation can help Veterans walk.

Peripheral Arterial Disease

VA Office of Research and Development120 participantsStarted Feb 2026

Decatur, Georgia, United States • Nashville, Tennessee, United States • Houston, Texas, United States

A Prospective Sub-Study of the Global Hypophosphatasia Registry

Randomized Clinical Trial for Ewing Amputation in the VA

Find Trials by Condition in Nashville

A Longitudinal Observational Study of the Natural History and Management of Patients With HCC

A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Registry of the Patient Experience for Carpal Tunnel Release

Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

A Study to Learn About the Study Medicine Called PF-07976016 in Adults With Obesity

A Study to Learn About the Study Medicine Called PF-07258669 in Older Adults Including Those at Risk of Malnutrition

A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

CLOZAPINE Response in Biotype-1

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

Pertuzumab, Trastuzumab, Hyaluronidase-zzxf and Enzalutamide for Treatment of Metastatic Castration-Resistant Prostate Cancer

A Study to Assess Recovery and Survival of Radiolabeled Apheresis Platelet Components Treated With the INTERCEPT Blood System for Platelets With LED Illuminator.

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2