Clinical Trials in Nashville

Showing 6961-6980 of 15,379 trials

Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

NCT01416428

The purpose of this study is to determine the maximum tolerated dose (MTD), activity, and safety of oprozomib in patients with hematologic malignancies.

Multiple MyelomaWaldenstrom Macroglobulinemia

Amgen210 participantsStarted Oct 2011

Scottsdale, Arizona, United States • Salinas, California, United States • Denver, Colorado, United States +16 more locations

COMPLETEDPhase 2< 1 mile

Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer

NCT00911820

There is no clear standard of care for metastatic stomach or esophageal cancer in the United States. The purpose of this research study is to determine the differences between two regimens of chemotherapy; Arm A: PCA (Cisplatin, Irinotecan and Bevacizumab) and Arm B: TPCA (Docetaxel, Cisplatin, Irinotecan and Bevacizumab). Docetaxel, Cisplatin, and Irinotecan are traditional chemotherapy drugs. Bevacizumab is an antibody (a protein that attacks a foreign substance in the body). Bevacizumab is believed to stop the formation of new blood vessels that carry nutrients to tumors. Both of the chemotherapy regimens (PCA and TPCA) have been studied in patients with esophageal and gastric cancer, and we are trying to determine if one regimen will keep your cancer from growing and improve how long you can live.

Esophageal CancerGastric CancerStomach Cancer

Dana-Farber Cancer Institute88 participantsStarted Jul 2009

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Nashville, Tennessee, United States +1 more locations

Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer

Find Trials by Condition in Nashville

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

Telehealth Mindfulness-Based Music and Songwriting for Parents of Children With Intellectual/Developmental Disabilities

A Phase 2 Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2

A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

An Investigational Immuno-therapy Trial of Pomalidomide and Low-dose Dexamethasone With or Without Elotuzumab to Treat Refractory and Relapsed and Refractory Multiple Myeloma (ELOQUENT-3)

Clinical Study to Evaluate Treatment With ORACEA® for Geographic Atrophy (TOGA)

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease

Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women

Clinical Performance of Two Commercial, Daily Disposable Contact Lenses

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140

A Study to Assess Long-term Safety, Tolerability and Efficacy of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Sodium Pyruvate Nasal Spray Treatment of COVID-19 Infection

A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE)

Diagnostic Accuracy Of Forced Oscillation Technique To Detect Lung Function Anomalies