Clinical Trials in Minneapolis

Showing 5541-5560 of 14,456 trials

Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial)

NCT04125732

The primary purpose of this trial is to determine the safety of XC001 (AdVEGFXC1) in patients who suffer from angina caused by coronary artery disease and have no other treatment options. Subjects in this study will receive one of four intramyocardial doses of XC001 that expresses human vascular endothelial growth factor (VEGF) which induces therapeutic angiogenesis (revascularization).

Coronary Artery DiseaseIschemiaAngina Refractory+2 more

XyloCor Therapeutics, Inc.41 participantsStarted Jan 2020

Stanford, California, United States • Washington D.C., District of Columbia, United States • Daytona Beach, Florida, United States +13 more locations

Not Yet RecruitingPhase 2< 1 mile

Ketamine Treatment for PTSD and MDD in TBI

NCT06228391

The goal of this clinical trial is to examine the use of sedative ketamine to treat depression and post-traumatic stress disorder (PTSD) in Veterans with mild to moderate traumatic brain injury (TBI). The main questions it aims to answer are: * Efficacy of ketamine to reduce symptoms of depression and/or PTSD * Safety of ketamine to treat depression and/or PTSD in TBI Participants will be randomly assigned to receive either ketamine or midazolam (active placebo) twice a week for 3 weeks. During participation, subjects will be interviewed, have lab tests, and complete rating scales, and questionnaires.

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury

Minneapolis Veterans Affairs Medical Center40 participantsStarted Mar 2024

Minneapolis, Minnesota, United States

Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial)

Ketamine Treatment for PTSD and MDD in TBI

Find Trials by Condition in Minneapolis

Accelerated Contrast-Enhanced High Resolution Whole Heart Cardiac MRI

Renal Impairment Study of PF-06700841

Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain

Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)

Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With OA of the Knee

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoarthritis

A Study of Octave System for Improving Lines and Wrinkles of the Décolleté

The Metformin Active Surveillance Trial (MAST) Study

Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study)

Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee

Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee

V160 2-Dose and 3-Dose Regimens in Healthy Cytomegalovirus (CMV) Seronegative Females (V160-002)

A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide

Study of Niraparib and TSR-042 in Recurrent Endometrial Cancer

EPI-743 for Mitochondrial Respiratory Chain Diseases

WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism

RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt