Clinical Trials in Massachusetts

Showing 1941-1960 of 15,316 trials

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

NCT04764474

An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.

Isocitrate Dehydrogenase Gene Mutation

Hutchmed46 participantsStarted Apr 2021

Orange, California, United States • Atlanta, Georgia, United States • Worcester, Massachusetts, United States +12 more locations

COMPLETEDPhase 318 miles

Initiating Early Control of Migraine Pain and Associated Symptoms

NCT04163185

AXS-07 is an oral, investigational medicine consisting of MoSEIC meloxicam and rizatriptan, which is being developed for the acute treatment of migraine with or without aura in adults. AXS-07 tablets are formulated to provide an enhanced rate of absorption of meloxicam. This study is designed to evaluate the efficacy and safety of AXS-07 compared to placebo. This is a randomized, double-blind, single-dose, placebo-controlled trial. Subjects who successfully complete the screening period and continue to meet all entry criteria will be randomly assigned to take one dose of either AXS-07 or placebo upon the earliest onset of migraine pain.

Migraine

Axsome Therapeutics, Inc.302 participantsStarted Oct 2019

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Mobile, Alabama, United States +38 more locations

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Initiating Early Control of Migraine Pain and Associated Symptoms

Find Trials by Condition in Massachusetts

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

A Study Of Changes In PD-L1 Expression During Preoperative Treatment With Nab-Paclitaxel And Pembrolizumab In Hormone Receptor-Positive Breast Cancer

Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA

Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer

EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery

Study of GS-4528 in Adults With Solid Tumors

More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

Early Onset Colorectal Cancer Detection