Clinical Trials in Massachusetts

Showing 1921-1940 of 15,316 trials

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

NCT04764474

An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.

Isocitrate Dehydrogenase Gene Mutation

Hutchmed46 participantsStarted Apr 2021

Orange, California, United States • Atlanta, Georgia, United States • Worcester, Massachusetts, United States +12 more locations

COMPLETEDPhase 226 miles

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

NCT05834738

The ASSIST study is a phase 2, double-blind, placebo-controlled crossover study to evaluate the safety and efficacy of atrasentan vs. placebo in subjects with IgA nephropathy (IgAN) while on background standard of care therapy and an SGLT2 inhibitor (SGLT2i).

IgA NephropathyImmunoglobulin A Nephropathy

Novartis Pharmaceuticals54 participantsStarted Jul 2023

Birmingham, Alabama, United States • Atlanta, Georgia, United States • Oak Brook, Illinois, United States +27 more locations

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

Find Trials by Condition in Massachusetts

Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

BCL2i CLAG-M in R/R Acute Myeloid Leukemia

A Study of PHN-010 in Patients With Advanced Solid Tumors

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

A Study Of Changes In PD-L1 Expression During Preoperative Treatment With Nab-Paclitaxel And Pembrolizumab In Hormone Receptor-Positive Breast Cancer

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Venetoclax Plus Inotuzumab for B-ALL

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

A Study With CIT-013 in HS Patients