Clinical Trials in Massachusetts

Showing 17221-17240 of 17,868 trials

Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses

NCT01085929

The incidence of skin and soft tissue infections has increased dramatically over the last decade, in part due to increased prevalence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). Incision and drainage (I\&D) is considered the primary intervention, however some clinicians prefer ultrasound guided needle aspiration (US Asp). The investigators performed a randomized trial comparing US Asp to I\&D for uncomplicated skin and soft tissue abscesses, with a subgroup analysis of patients with CA-MRSA.

AbscessCellulitis

University of Massachusetts, Worcester101 participantsStarted Aug 2008

Boston, Massachusetts, United States • Worcester, Massachusetts, United States

COMPLETEDPhase 214 miles

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

NCT00642174

This trial is designed as a phase 2 randomized, double-blind double dummy, active comparator controlled, two-period two-arm crossover study to enroll 40 patients across multiple centers. The study will compare platelet function following a prasugrel loading dose and 1 week of prasugrel maintenance therapy with high-dose clopidogrel loading dose and 1 week of high-dose clopidogrel maintenance therapy in patients with drug treated type 2 diabetes mellitus who have coronary artery disease. Various assays of platelet function will be used in this study. Platelet function will be studied using the following assays: Accumetrics VerifyNowTM P2Y12, Light Transmittance Aggregometry (LTA), Vasodilator-associated stimulated phosphoprotein (VASP), and Thromboelastography (TEG)-platelet mapping.

Diabetes MellitusCoronary Artery Disease

Eli Lilly and Company35 participantsStarted Apr 2008

Jacksonville, Florida, United States • Worcester, Massachusetts, United States • New York, New York, United States +1 more locations

Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

Find Trials by Condition in Massachusetts

An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications.

Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Nonmalignant Hematologic Disease

Open-Label, Pilot Study of TG100801 in Patients With Choroidal Neovascularization Due to AMD

Complications of Age-Related Macular Degeneration Prevention Trial

Study to Determine the Effects Treatment With Amlexanox 0.5% Oral Rinse Solution on Oral Mucositis Associated With Radiation Therapy for Cancer of the Head and Neck Region

Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiforme

ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH)

Safety and Efficacy of Avonex in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Evaluate Clinical Research From Commerical Oral Care Products

Diabetes Control and Complications Trial (DCCT)

A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis

Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathy

Interactive Voice Response (IVR) for Methadone Patients

Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background

Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD)

Study of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

A Phase I Study of BMS-275183 (Oral Taxane) Given on a Daily Schedule in Combination With Esomeprazole (Nexium) in Patients With Advanced Cancer

A Phase I Study of BMS-275183 Given on a Daily Schedule in Patients With Advanced Malignancies