Clinical Trials in Massachusetts

Showing 14721-14740 of 17,868 trials

Investigation of a Behavioral Substitute for Sunbathing

NCT00403377

RATIONALE: Understanding why sunbathers use or don't use sunless tanning products may help doctors plan effective ways to prevent skin cancer caused by sunbathing. PURPOSE: This phase I/II trial is studying attitudes about the use of sunless tanning products and how well sunless tanning products work as a substitute for sunbathing in healthy participants.

Melanoma (Skin)Skin Cancer

University of Massachusetts, Worcester307 participantsStarted Apr 2006

Worcester, Massachusetts, United States

COMPLETEDPhase 321 miles

S0106 Cytarabine and Daunorubicin w/ or w/o Gemtuzumab Followed By HD Cytarabine and Either Gemtuzumab or Nothing in de Novo AML

NCT00085709

RATIONALE: Drugs used in chemotherapy, such as cytarabine and daunorubicin, work in different ways to stop cancer cells from dividing so they stop growing and die. Monoclonal antibodies, such as gemtuzumab ozogamicin, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining chemotherapy with gemtuzumab ozogamicin may kill more cancer cells. It is not yet known whether induction therapy using cytarabine and daunorubicin is more effective with or without gemtuzumab ozogamicin or whether postconsolidation therapy using gemtuzumab ozogamicin is more effective than no additional therapy in treating de novo (first occurrence) acute myeloid leukemia. PURPOSE: This randomized phase III trial is comparing two different regimens of chemotherapy and monoclonal antibody therapy to see how well they work in treating patients with previously untreated de novo acute myeloid leukemia.

Leukemia

SWOG Cancer Research Network637 participantsStarted Jul 2004

Anchorage, Alaska, United States • Fort Smith, Arkansas, United States • Little Rock, Arkansas, United States +276 more locations

Investigation of a Behavioral Substitute for Sunbathing

S0106 Cytarabine and Daunorubicin w/ or w/o Gemtuzumab Followed By HD Cytarabine and Either Gemtuzumab or Nothing in de Novo AML

Find Trials by Condition in Massachusetts

Oral and Non-insulin Injected Hypoglycemic Therapy Utilization Patterns

Burn Outcomes in Young Adult Burn Survivors

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Transcutaneous Immunization With an Attenuated Listeria Monocytogenes Vector Vaccine

A Phase 1 Study of IMGN289 in Adult Patients With EGFR-positive Solid Tumors

Study of Liberty Program on Women's Health and Intimate Partner Violence

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

Cognitive-behavior Therapy for MS-Related Chronic Pain

Effect of Daily Low Dose Aspirin on Exhaled Inflammatory Mediators in Normal Subjects

Calcium, Phosphate, Renal Impairment and Coronary Artery Disease in the Cardio-renal Syndrome, The CAPRICORN-CRS Study

A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation

A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder

Remote Ischemic Preconditioning in Cardiac Surgery Trial

Perindopril Amlodipine for the Treatment of Hypertension

Hormone Receptor Positive Metastatic Breast Cancer (HR+ mBC) BIIB021 Plus Aromasin Schedule Finding

AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR