Clinical Trials in Massachusetts

Showing 5021-5040 of 17,868 trials

HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose

NCT05136885

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen E will evaluate the safety and efficacy of a single study drug, SLS-005 (Trehalose injection, 90.5 mg/mL for intravenous infusion) in participants with ALS.

Amyotrophic Lateral Sclerosis

Merit E. Cudkowicz, MD161 participantsStarted Feb 2022

Boston, Massachusetts, United States

Active Not RecruitingNA26 miles

Mohala Na Pua: Community-driven Drug Prevention

NCT06971003

The goal of this clinical trial is to learn if a substance use prevention intervention decreases substance use, increases resistance skill use, and decreases substance use risk in intermediate school students. The main questions it aims to answer: Does the intervention decrease 30-day substance use? Does the intervention increase 30-day resistance skill use? Participants will be asked to participate in the intervention and provide their self-reported answers to behavioral questions before and after the intervention.

Adolescent

Judge Baker Children's Center130 participantsStarted Apr 2025

Kaneohe, Hawaii, United States • Boston, Massachusetts, United States

COMPLETEDPhase 226 miles

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

NCT00179673

Subjects who qualify will receive lenalidomide daily on days 1-21 of every 28-day cycle. Treatment will continue for up to 52 weeks or until disease progression; subjects who achieve a Complete Response (CR) will receive an additional 2 cycles of treatment prior to discontinuation. Subjects will be followed for progression free survival following discontinuation from the treatment phase

Non-Hodgkins Lymphoma

Celgene43 participantsStarted Jun 2005

Scottsdale, Arizona, United States • Berkeley, California, United States • Fountain Valley, California, United States +12 more locations

HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose

Mohala Na Pua: Community-driven Drug Prevention

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

Find Trials by Condition in Massachusetts

Pediatric ACL: Understanding Treatment Options

PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study

A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery

Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer

Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

SARS-CoV-2 and Influenza A/B in Point-of-Care and Non-Laboratory Settings

Exercise to Augment TMS in Those With Treatment Resistant Depression

Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)

Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy

Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma

A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease

STEM-Parkinson's Disease

A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants

A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.