Clinical Trials in Massachusetts

Showing 2001-2020 of 15,316 trials

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

NCT05837104

This is a randomized, double-blind, placebo-controlled proof-of-concept clinical trial to assess the efficacy and safety of Magnesium-vitamin B6in combination with treatment as usual for treating symptoms of depression, stress, and anxiety in patients with first episode bipolar I disorder.

Bipolar I DisorderDepression, AnxietyStress

Mclean Hospital40 participantsStarted Dec 2023

Belmont, Massachusetts, United States

COMPLETEDPhase 326 miles

Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2

NCT03505099

To evaluate the safety and efficacy of intravenous onasemnogene abeparvovec-xioi in pre-symptomatic patients with SMA and 2 or 3 copies SMN2

Spinal Muscular Atrophy

Novartis Gene Therapies30 participantsStarted Apr 2018

Los Angeles, California, United States • Aurora, Colorado, United States • Orlando, Florida, United States +13 more locations

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2

Find Trials by Condition in Massachusetts

Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

A Study of Abemaciclib (LY2835219) in Participants With Non-Small Cell Lung Cancer or Breast Cancer

Deferoxamine for the Prevention of Cardiac Surgery-Associated Acute Kidney Injury

Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial)

Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer

Optimizing the Safety of Inter-Hospital Transfer

HKI-272 for HER2-Positive Breast Cancer and Brain Metastases

Early Postoperative Function After Open Versus Ultrasound-Guided Trigger Finger Release

A Phase I/II Study to Assess the Safety and Efficacy of Vaccinations With Allogeneic Dendritic Cells: Autologous Tumor-Derived Cells Subjected to Electrofusions in Patients With AJCC Stage IV Renal Cell Carcinoma

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

Safety and Preliminary Efficacy of BNT314 in Cancer Patients With Malignant Solid Tumors

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

A Study of Mezagitamab in Adults With Primary Immunoglobulin A Nephropathy Receiving Stable Background Therapy

Dose Ranging, Switch Study of Islatravir (MK-8591) and Ulonivirine (MK-8507) Once-Weekly in Virologically-Suppressed Adults With Human Immunodeficiency Virus Type 1 (HIV-1) [MK-8591-013]