Clinical Trials in Florida

Showing 1641-1660 of 12,796 trials

TNF-α Treatment of Blast-Induced Tinnitus

NCT04066348

The purpose of this multi-site research study is to determine if Etanercept, compared to a placebo, significantly reduces the severity of tinnitus (ringing in the ears) associated with history of blast and/or noise exposure or associated with Traumatic Brain Injury (TBI) and/or concussion. Individuals who qualify will be randomized into one of two groups: The group receiving the medication Etanercept or the group receiving a saline solution placebo.

Tinnitus, Noise Induced

Wayne State University88 participantsStarted Jul 2022

Celebration, Florida, United States • Coral Gables, Florida, United States • Detroit, Michigan, United States +1 more locations

Active Not RecruitingPhase 149 miles

A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)

NCT05403450

The primary purpose of the study is to assess safety, and to identify the recommended phase 2 dose (RP2D) of tolinapant in combination with oral decitabine/cedazuridine in Phase 1 and to assess preliminary efficacy as determined by overall response rate (ORR) in Phase 2. As no safe and tolerable dosing for the combination of tolinapant and decitabine/cedazuridine was identified based on protocol defined criteria, Sponsor decided to halt recruitment and to not conduct Phase 2 of the study.

Relapsed/Refractory Peripheral T-cell Lymphoma

Taiho Oncology, Inc.33 participantsStarted Feb 2023

Duarte, California, United States • Los Angeles, California, United States • Stanford, California, United States +43 more locations

TNF-α Treatment of Blast-Induced Tinnitus

A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)

Find Trials by Condition in Florida

A Phase 2, Open-Label, Extension Study to Evaluate Long Term Safety and Clinical Activity of Briquilimab in Participants From Jasper-Sponsored Chronic Urticaria Trials

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza

A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

IMAAGEN: Impact of Abiraterone Acetate in Prostate-Specific Antigen

Study to Assess the Safety and Efficacy of Subcutaneously Injected Risankizumab in Adult Participants With Genital or Scalp Psoriasis

Study of the Safety and Neuroprotective Capacity of Scp776 in Acute Ischemic Stroke

Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)

Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction

A Study to Assess the Efficacy and Safety of Daily OM-85 in Young Children With Recurrent Wheezing

A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE

A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

A Study of Rilzabrutinib in Adult Patients With Immune Thrombocytopenia (ITP)

A Treatment Effectiveness Study Among SLE Patients Receiving Anifrolumab in Routine Clinical Practice