Clinical Trials in Florida

Showing 561-580 of 12,796 trials

A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

NCT07323654

This Phase 2b study is designed to evaluate the safety and efficacy of KT-621 in participants with uncontrolled moderate to severe eosinophilic asthma. The main goals of this study are to investigate how effective KT-621 is at treating uncontrolled moderate to severe eosinophilic asthma, the safety and tolerability of KT-621, and how KT-621 behaves in the body.

Eosinophilic Asthma

Kymera Therapeutics, Inc.264 participantsStarted Jan 2026

Redding, California, United States • Upland, California, United States • Miami, Florida, United States +14 more locations

RECRUITINGPhase 357 miles

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT06393374

This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TPC) in participants with triple-negative breast cancer (TNBC) who received neoadjuvant therapy and did not achieve a pathological complete response (pCR) at surgery. The primary objective is to compare sacituzumab tirumotecan plus pembrolizumab to TPC (pembrolizumab or pembrolizumab plus capecitabine) with respect to invasive disease-free survival (iDFS) per investigator assessment. It is hypothesized that sacituzumab tirumotecan plus pembrolizumab is superior to TPC with respect to iDFS per investigator assessment.

Triple-Negative Breast Cancer

Merck Sharp & Dohme LLC1,530 participantsStarted Jun 2024

Mobile, Alabama, United States • Chandler, Arizona, United States • Fountain Valley, California, United States +284 more locations

A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Find Trials by Condition in Florida

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults

Evaluation of the Efficacy and Safety of LevoCept

Nab-Paclitaxel + Cisplatin + Gemcitabine in Untreated Metastatic Pancreatic Adenocarcinoma

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Neuroendocrine Tumors

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)

Pyruvate Kinase Deficiency Global Longitudinal Registry

Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis