Clinical Trials in Detroit

Showing 6301-6320 of 14,997 trials

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

NCT05153408

This is a Phase 1/2, open-label, first-in-human (FIH) study is designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of BLU-701 as monotherapy or in combination with either osimertinib or platinum-based chemotherapy in patients with EGFRm NSCLC.

Lung NeoplasmCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+24 more

Blueprint Medicines Corporation20 participantsStarted Jan 2022

Boston, Massachusetts, United States • Detroit, Michigan, United States • New York, New York, United States +4 more locations

TERMINATEDPhase 3< 1 mile

A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection

NCT02450331

This Phase III, open-label, randomized, multicenter study is to evaluate the efficacy and safety of adjuvant treatment with atezolizumab compared with observation in participants with muscle-invasive UC who are at high risk for recurrence following resection. Eligible participants were randomized by a 1:1 ratio into atezolizumab group or control group.

Carcinoma, Transitional Cell

Hoffmann-La Roche809 participantsStarted Oct 2015

Scottsdale, Arizona, United States • Los Angeles, California, United States • Los Angeles, California, United States +183 more locations

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection

Find Trials by Condition in Detroit

A Study of LNK01002 in Patients With Primary or Secondary Myelofibrosis,Polycythemia Vera or Acute Myeloid Leukemia

Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer

Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia

Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach

Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer

Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue Sarcoma

High-Dose Melphalan Plus Peripheral Stem Cell Transplantation in Treating Patients With Primary Systemic Amyloidosis

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

Paclitaxel and Carboplatin in Treating Patients With Locally Advanced or Metastatic Renal Cell Cancer

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Long-term Treatment of Moderate to Severe Glabellar Lines and Lateral Canthal Lines

Alemtuzumab Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Lymphocytic Leukemia

Glioma Supra Marginal Incision Trial

Treatment of Moderate to Severe Glabellar Lines

Chemotherapy in Treating Women With Previously Treated Metastatic Breast Cancer

Mobile Cardiac Telemetry and Advanced Multi-Parameter Monitoring in PatientS Wearing a Novel Device With Biometric Based Medications Changes

Sustained Humoral and Cell-Mediated Immunogenicity of COVID-19 Vaccines in Patients With Inflammatory Bowel Disease

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2)