Clinical Trials in Detroit

Showing 6321-6340 of 19,719 trials

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL

NCT05233033

This Phase 1a/1b study will evaluate the safety, tolerability and the pharmacokinetics/ pharmacodynamics (PK/ PD) of KT-413 in patients with R/R NHL. The Phase 1a stage of the study will explore escalating doses of single-agent KT-413. The Phase 1b stage will be split into 2 expansion cohorts to further characterize the safety, tolerability and the pharmacokinetics/ pharmacodynamics (PK/ PD) of KT-413 in MYD88 mutant and MYD88 wild-type R/R DLBCL.

Non Hodgkin LymphomaDiffuse Large B Cell LymphomaDLBCL+1 more

Kymera Therapeutics, Inc.7 participantsStarted Jun 2022

Washington D.C., District of Columbia, United States • Louisville, Kentucky, United States • Detroit, Michigan, United States +5 more locations

COMPLETEDPhase 3< 1 mile

A Clinical Trial Evaluating Efficacy and Safety of MC2-01 Cream

NCT03308799

This trial is a randomized, investigator-blind, multicentre, vehicle- and comparator-controlled, parallel-group trial with the purpose of evaluating efficacy, safety and convenience of the MC2-01 cream.

Psoriasis Vulgaris

MC2 Therapeutics794 participantsStarted Oct 2017

Detroit, Michigan, United States • Fridley, Minnesota, United States • Spokane, Washington, United States

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL

A Clinical Trial Evaluating Efficacy and Safety of MC2-01 Cream

Find Trials by Condition in Detroit

A Phase 4, Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma

ET-01 in Subjects With Lateral Canthal Lines, LCL-210

A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance

GKT137831 in IPF Patients with Idiopathic Pulmonary Fibrosis

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

Preliminary Evaluation of a RCMP to Predict Failure of Maxillomandibular Advancement Surgery for OSA

Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health

Study of PULSAR-ICI +/- IMSA101 in Patients with Oligoprogressive Solid Tumor Malignancies

Efficacy and Safety of MK-1942 as an Adjunct Therapy in Participants With Mild to Moderate Alzheimer's Disease Dementia (MK-1942-008)

Pragmatic Trial Examining Oxygenation Prior to Intubation

Phase 1b, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Chronic Inducible Urticaria

A Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations

SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma

Study of Efficacy of Ribociclib After Progression on CDK4/6 Inhibition in Patients With HR+ HER2- Advanced Breast Cancer

SpineJack System Postmarket Registry

A Study to Investigate the Prevention of COVID-19 WithVYD222 in Adults with Immune Compromise and in Participants Aged 12 Years or Older Who Are At Risk of Exposure to SARS-CoV-2

Study Evaluating the Efficacy and Safety of OCS-01 Eye Drops in Subjects Following Cataract Surgery

A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease