Clinical Trials in Detroit

Showing 3621-3640 of 9,449 trials

Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations

NCT01262625

This randomized, controlled, diagnostic, multicenter trial will compare two diagnostic imaging pathways--coronary computed tomography angiography (CCTA) and single photon emission tomography (SPECT) myocardial perfusion imaging (MPI)--to determine the incidence of major adverse coronary events (MACE), defined as myocardial infarction (MI) or cardiac-related death, and cross-over to revascularization. CCTA may be used to direct patients with symptoms of stable angina or angina equivalent to optimal medical therapy (OMT). The use of CCTA as a diagnostic tool for angina symptoms will be associated with no increase in MACE or revascularization, decreased cost, reduced risks (e.g., less radiation exposure), additional insights into alternate explanations of chest pain, and increased cost-effectiveness in comparison with use of SPECT MPI/invasive coronary angiography (ICA).

Chest PainStable Angina Pectoris, CCS Class I to IIIAngina Equivalent+1 more

American College of Radiology1,050 participantsStarted May 2011

Decatur, Georgia, United States • Detroit, Michigan, United States • Salem, Virginia, United States

WITHDRAWNPhase 1/2< 1 mile

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

NCT04151563

This study is for participants with Non-small Cell Lung Cancer that has spread or has reoccurred after failure of Chemotherapy and Immunotherapy

Carcinoma, Non-small Cell Lung Cancer

Bristol-Myers SquibbStarted Apr 2021

Detroit, Michigan, United States • Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina • Buenos Aires, Distrito Federal, Argentina +20 more locations

Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

Find Trials by Condition in Detroit

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma

Verily Watch Cardio (AF and ECG) Study

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee

Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson's Disease Related Constipation

A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Relapsing Forms of Multiple Sclerosis

Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

Sinusoidal Obstruction Syndrome for Stem Cell Transplant Patients Biomarker Study

MSB11022 in Moderate to Severe Chronic Plaque Psoriasis

Percutaneous Hepatic Perfusion in Patients With Hepatic-dominant Ocular Melanoma

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis

A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Moderate-to-Severe Atopic Hand and Foot Dermatitis (Liberty-AD-HAFT)

A Study of LY3410738 in Healthy Adult Participants