Clinical Trials in Dallas

Showing 7181-7200 of 17,468 trials

Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition

NCT02579460

The purpose of this study is to elucidate mechanisms whereby oxidative stress induced by acute reflux esophagitis: 1) activates p38 to regulate proteins that control the G1/S cell cycle checkpoint, and 2) activates HIFs (hypoxia inducible factors) to cause autocrine VEGF (vascular endothelial growth factor) signaling that triggers the EMT (epithelial-mesenchymal-transition) program in Barrett's esophagus.

Barrett's EsophagusGastroesophageal Reflux Disease

Dallas VA Medical Center15 participantsStarted Nov 2015

Dallas, Texas, United States

COMPLETEDPhase 2< 1 mile

LY3023414 and Prexasertib in Metastatic Triple-negative Breast Cancer

NCT04032080

This study evaluates efficacy of LY3023414 and prexasertib in patients with metastatic triple negative breast cancer.

Triple Negative Breast Cancer

Baylor Research Institute10 participantsStarted Sep 2019

Dallas, Texas, United States

COMPLETEDPhase 3< 1 mile

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

NCT00709865

The purpose of the current study is to assess the safety and tolerability of intravenous tonapofylline.

Renal InsufficiencyCongestive Heart Failure

Biogen420 participantsStarted Jul 2008

Huntsville, Alabama, United States • Mobile, Alabama, United States • Fort Smith, Arkansas, United States +186 more locations

Reflux-Induced Oxidative Stress in Barrett's Esophagus: Response, Repair, and Epithelial-Mesenchymal-Transition

LY3023414 and Prexasertib in Metastatic Triple-negative Breast Cancer

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

Find Trials by Condition in Dallas

Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia

End-of-Life Care for African Americans: An Outpatient Intervention

A Study of Duvelisib in Participants With Refractory Indolent Non-Hodgkin Lymphoma

A Long-Term Extension Trial in Participants With Atopic Dermatitis Who Participated in Previous EDP1815 Trials

Family Assessment Motivation, and Linkage Intervention (FAMLI)

Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis

Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

PCI Treatment/Gemcitabine & Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Extrahepatic Bile Duct Cancer

Cabozantinib as a Targeted Strategy to Reverse Carfilzomib Resistance in Refractory Multiple Myeloma

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis

Real World Evaluation of the Effectiveness of AZD7442 for Prevention of SARS-CoV-2

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis

Impact of Acetaminophen on Performance of Guardian™ Sensor (3) in Adults

Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 2