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Discover 15,592 clinical trials near Colorado. Find research studies in your area.
Showing 13181-13200 of 15,592 trials
NCT01145872
This research proposal is intended to elucidate the efficacy and mechanisms underlying Mindfulness Based Cognitive Therapy (MBCT) in a population in remission from recurrent Major Depressive Disorder (MDD). The first objective of the study is to replicate previous studies' findings of MBCT's effects on decreasing depressive symptoms and depression relapse rates. However, this proposal aims to make a novel contribution to the literature by using a randomized, controlled design, and comparing the effects of MBCT to an active control condition (ACC). The use of a well-designed ACC will enable us to control for confounding variables such as social support and expected outcomes, thus allowing us to determine whether elements specific to MBCT lead to its salutary effects (Aim 1). Previous MBCT studies have largely relied on self-report measurement methodologies, limiting valid conclusions about the nature of MBCT. Further, few studies have examined the mechanisms underlying effects of MBCT on depressive symptoms and relapse. Theoretical considerations and preliminary empirical evidence suggest emotional, physiological, and cognitive functioning to be promising mechanisms of MBCT. Therefore, the investigators propose to assess each of these potential mechanisms of MBCT using self-report, autonomic physiological, and reaction time tasks (Aim 2). Collectively, these aims are expected to strengthen the evidence base for MBCT while cultivating a scientific model for its effects and mechanisms on decreasing depressive symptoms and depression relapse rates.
NCT01502475
In this protocol, the investigators proposed to assess the Complementary Alternative Medicine (CAM) usage patterns in a Veteran population using a CAM survey developed by Dr. Hernandez and colleagues. This survey, the Complementary, Alternative and Conventional Medicines Attitudes Scale (CACMAS), is a brief, self-report questionnaire that assesses medical use patterns, as well as attitudes about medical treatment and the relationship among these. The CACMAS will assess the potential role of individual beliefs and attitudes towards complementary and conventional medicine usage patterns, and possibly indicate how this scale might be used to predict optimal treatment offerings for a particular population given attitudes about medical treatments.