Sweat Evaporimeter Measurement

Exclusion Criteria

• •1. Patients who are participating in clinical trials evaluating the safety, efficacy or clinical outcome of drugs that may alter the CFTR Cl channel function will be excluded.
• •2. Any subject with a known hypersensitivity to any agonist used in the study or subjects receiving any drug (e.g. theophylline, antihypertensive agent) that might interfere with the investigations.
• •3. Subjects with active dermatitis or other chronic skin condition such as psoriasis or a strong allergic history.
• •4. Patients with a history of cardiac disease (including arrhythmias or hypertrophic obstructive cardiomyopathy).
• •5. CF patients with severe malnutrition (BMI\<18 kg/m2).
• •6. CF patients with severe lung disease (FEV1\<25%).
• •7. Subject who has been treated for pulmonary exacerbation or other acute illness within one week of the study procedure.
• •8. Any medical condition that, in the opinion of the investigator, will interfere with accurate conduct of the study.
• •9. Subjects who are pregnant or lactating.
• •10. Subject who is not able to stop inhalation therapy of β -adrenergic drugs 12 hrs before starting each test.