Clinical Trials in Cleveland

Showing 1681-1700 of 9,497 trials

Pectoralis and Serratus Muscle Blocks

NCT03743194

The overall research plan is PECS/SAP blocks with liposomal bupivacaine improve the Overall Benefit Analgesia Score averaged over the postoperative days 1, 2, and 3. A 20% reduction on geometric means (i.e., true ratio of geometric means of 0.80) in OBAS will be considered the minimal clinically important benefit.

Post Operative Pain Control

The Cleveland Clinic210 participantsStarted Dec 2021

Cleveland, Ohio, United States

COMPLETEDPhase 4< 1 mile

EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients

NCT04998604

Primary Objective -To evaluate the efficacy of dupilumab compared to omalizumab in reducing the polyp size and improving sense of smell Secondary Objectives * To evaluate the efficacy of dupilumab in improving chronic rhinosinusitis with nasal polyps (CRSwNP) symptoms at Week 24 compared to omalizumab * To evaluate the efficacy of dupilumab in improving CRSwNP total symptom score (TSS) at Week 24 compared to omalizumab * To evaluate the effect of dupilumab on health related quality of life (HRQoL) at week 24 compared to omalizumab * To evaluate the efficacy of dupilumab in improving nasal peak inspiratory flow at Week 24 compared to omalizumab * To evaluate the effect of dupilumab on CRSwNP overall disease severity at Week 24 compared to omalizumab * To evaluate the safety of dupilumab and omalizumab

Chronic Rhinosinusitis With Nasal PolypsAsthma

Sanofi360 participantsStarted Sep 2021

Los Angeles, California, United States • Tampa, Florida, United States • Chicago, Illinois, United States +84 more locations

Pectoralis and Serratus Muscle Blocks

EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients

Find Trials by Condition in Cleveland

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy

A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease

A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular Edema

A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia

Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata

A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI

Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection

Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:

Non-Operative Management and Early Response Assessment in Rectal Cancer